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- W2006134426 abstract "Abstract Emerging evidence suggests that the proapoptotic kinase mammalian sterile 20–like kinase 2 (MST2) acts in a novel tumor suppression pathway. Recently, we showed that Raf-1 kinase sequesters and inhibits MST2 and that this event is critical for Raf-mediated cell survival. In this review, we summarize Raf control of MST2 and we outline a novel pathway involving the downstream effector proteins Salvador and Warts/Lats that may act to limit the positive effects of Raf–mitogen-activated protein kinase signaling in cancer cells." @default.
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- W2006134426 date "2005-07-01" @default.
- W2006134426 modified "2023-09-23" @default.
- W2006134426 title "Mammalian Sterile 20–Like Kinases in Tumor Suppression: An Emerging Pathway" @default.
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- W2006134426 doi "https://doi.org/10.1158/0008-5472.can-05-1453" @default.
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