Matches in SemOpenAlex for { <https://semopenalex.org/work/W2006161971> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W2006161971 endingPage "584" @default.
- W2006161971 startingPage "573" @default.
- W2006161971 abstract "Abstract The action of dimorpholamine on crayfish neuromuscular junction was studied to obtain a clue to the mechanism of action of the drug on mammalian central nervous system. Excitatory and inhibitory junctional potentials (e.j.p.s and i.j.p.s) were recorded with an intracellular or extracellular microelectrode. Dimorpholamine (1.5 × 10−4 g ml ) increased the amplitude of intra- and extracellularly recorded e.j.p.s to 2–4 times the control size. The drug increased the input resistance of muscle fibers by 20–60 %. Dimorpholamine markedly increased the probability of quantal release of excitatory transmitter, while the quantum size of the extracellular e.j.p.s was slightly reduced by the drug. It was concluded that the main mechanism of action of dimorpholamine to increase the size of e.j.p.s is an increase in the amount of excitatory transmitter released from the terminals by nerve impulses. Under the action of dimorpholamine, the amplitude of intracellular i.j.p.s was increased by a factor of 1.2–3.0, while the sensitivity of the postsynaptic membrane to γ-aminobutyric acid was not altered by the drug. The main mechanism of action of dimorpholamine to augment the i.j.p. size is attributed to the increase in membrane resistance of muscle fibers. The possibility that dimorpholamine may affect non-cholinergic synapses in mammalian central nervous system is discussed." @default.
- W2006161971 created "2016-06-24" @default.
- W2006161971 creator A5014314344 @default.
- W2006161971 creator A5034525835 @default.
- W2006161971 date "1972-07-01" @default.
- W2006161971 modified "2023-10-16" @default.
- W2006161971 title "The effect of dimorpholamine on crayfish neuromuscular junction" @default.
- W2006161971 cites W1916793833 @default.
- W2006161971 cites W1968711633 @default.
- W2006161971 cites W1968938034 @default.
- W2006161971 cites W2000552368 @default.
- W2006161971 cites W2002819801 @default.
- W2006161971 cites W2009384667 @default.
- W2006161971 cites W2035282305 @default.
- W2006161971 cites W2039005332 @default.
- W2006161971 cites W2048035298 @default.
- W2006161971 cites W2049181260 @default.
- W2006161971 cites W2055871381 @default.
- W2006161971 cites W2055947351 @default.
- W2006161971 cites W2060226757 @default.
- W2006161971 cites W2076355504 @default.
- W2006161971 cites W2080304818 @default.
- W2006161971 cites W2085263063 @default.
- W2006161971 cites W2102492718 @default.
- W2006161971 cites W2111920067 @default.
- W2006161971 cites W2186457177 @default.
- W2006161971 cites W2229435899 @default.
- W2006161971 cites W2325546854 @default.
- W2006161971 cites W2985956097 @default.
- W2006161971 cites W392044536 @default.
- W2006161971 doi "https://doi.org/10.1016/0028-3908(72)90013-5" @default.
- W2006161971 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/4403079" @default.
- W2006161971 hasPublicationYear "1972" @default.
- W2006161971 type Work @default.
- W2006161971 sameAs 2006161971 @default.
- W2006161971 citedByCount "7" @default.
- W2006161971 crossrefType "journal-article" @default.
- W2006161971 hasAuthorship W2006161971A5014314344 @default.
- W2006161971 hasAuthorship W2006161971A5034525835 @default.
- W2006161971 hasConcept C169760540 @default.
- W2006161971 hasConcept C185592680 @default.
- W2006161971 hasConcept C2777240379 @default.
- W2006161971 hasConcept C2781403440 @default.
- W2006161971 hasConcept C505870484 @default.
- W2006161971 hasConcept C86803240 @default.
- W2006161971 hasConceptScore W2006161971C169760540 @default.
- W2006161971 hasConceptScore W2006161971C185592680 @default.
- W2006161971 hasConceptScore W2006161971C2777240379 @default.
- W2006161971 hasConceptScore W2006161971C2781403440 @default.
- W2006161971 hasConceptScore W2006161971C505870484 @default.
- W2006161971 hasConceptScore W2006161971C86803240 @default.
- W2006161971 hasIssue "4" @default.
- W2006161971 hasLocation W20061619711 @default.
- W2006161971 hasLocation W20061619712 @default.
- W2006161971 hasOpenAccess W2006161971 @default.
- W2006161971 hasPrimaryLocation W20061619711 @default.
- W2006161971 hasRelatedWork W1976980751 @default.
- W2006161971 hasRelatedWork W1988013338 @default.
- W2006161971 hasRelatedWork W2006730088 @default.
- W2006161971 hasRelatedWork W2023251390 @default.
- W2006161971 hasRelatedWork W2027308819 @default.
- W2006161971 hasRelatedWork W2167132919 @default.
- W2006161971 hasRelatedWork W2461593390 @default.
- W2006161971 hasRelatedWork W2524962099 @default.
- W2006161971 hasRelatedWork W2802976864 @default.
- W2006161971 hasRelatedWork W4235981111 @default.
- W2006161971 hasVolume "11" @default.
- W2006161971 isParatext "false" @default.
- W2006161971 isRetracted "false" @default.
- W2006161971 magId "2006161971" @default.
- W2006161971 workType "article" @default.