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• W2006162395 abstract "The degradation mechanism of a series of polyglycolic/polylactic acid, (PGA/PLA), homo and copolymers synthesized as in Part 11, has been studied vitro. An in vitro test model similar to that described in a previous study9, was used. The effects of time, temperature and pH on the rate and mechanism of degradation were elucidated. The degree of degradation was monitored molecularly by gel permeation chromatography (g.p.c.), tensile strength determination and mass loss measurements. The mechanism of degradation is shown to be by hydrolysis. The copolymers of PGA and PLA are shown to have a wide range of degradation rates governed by the hydrophilic/hydrophobic balance and crystallinity of the respective copolymer. The effect of the glass transition temperature (Tg) of PGA on its sensitivity to degradation is also demonstrated." @default.
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• W2006162395 date "1981-04-01" @default.
• W2006162395 modified "2023-10-06" @default.
• W2006162395 title "Biodegradable polymers for use in surgery — poly(glycolic)/poly(Iactic acid) homo and copolymers: 2. In vitro degradation" @default.
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• W2006162395 doi "https://doi.org/10.1016/0032-3861(81)90168-3" @default.
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