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- W2006184423 abstract "A series of novel 1,3-benzodiazapine based D1 antagonists was designed according to the understanding of pharmacophore models derived from SCH 23390 (1b), a potent and selective D1 antagonist. The new design features an achiral cyclic-amidine that maintains desired basicity. Solid phase synthesis was developed for SAR development of the novel dopamine antagonists." @default.
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- W2006184423 date "2009-09-01" @default.
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- W2006184423 title "Design and discovery of 1,3-benzodiazepines as novel dopamine antagonists" @default.
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- W2006184423 doi "https://doi.org/10.1016/j.bmcl.2009.07.012" @default.
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