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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2006192016> ?p ?o ?g. }

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• W2006192016 abstract "Adenine nucleotide translocator-1 (ANT-1), encoded by chromosome 4 (4q34-35 locus), is a component of the mitochondrial permeability transition pores that are involved in apoptotic mechanisms. We studied muscle biopsies from seven individuals with autosomal dominant progressive external ophthalmoplegia caused by ANT-1 mutations. We found no instance of terminal deoxynucleotidyltransferase-mediated dUTP nick end labeling (TUNEL) positivity nor significant expression of apoptosis-related proteins. Furthermore, there was no morphological evidence of apoptosis at the ultrastructural level. Thus, degeneration of muscle in this disorder is nonapoptotic." @default.
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• W2006192016 date "2002-07-29" @default.
• W2006192016 modified "2023-09-24" @default.
• W2006192016 title "Lack of apoptosis in patients with progressive external ophthalmoplegia and mutated adenine nucleotide translocator-1 gene" @default.
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• W2006192016 doi "https://doi.org/10.1002/mus.10172" @default.
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