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• W2006194890 abstract "Synthesis of first generation non-hydrolysable C-phosphonate GPI analogs, viz., 6-O-(2-amino-2-deoxy-α-d-glucopyranosyl)-d-myo-inositol-1-O-(sn-3,4-bis(palmitoyloxy)butyl-1-phosphonate) and 6-O-(2-amino-2-deoxy-α-d-glucopyranosyl)-d-myo-inositol-1-O-(sn-2,3-bis(palmitoyloxy)propyl-1-phosphonate) 23b, is reported. The target compounds were synthesized by the coupling of α-pseudodisaccharide 21 with phosphonic acids 18a and 18b respectively in quantitative yield followed by de-protection. These synthetic C-phosphonate GPI-probes were resistant to phosphatidylinositol specific phospholipase C (PI-PLC) and also showed moderate inhibition of the enzyme activity." @default.
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• W2006194890 date "2014-01-01" @default.
• W2006194890 modified "2023-10-17" @default.
• W2006194890 title "Synthesis of non-hydrolysable mimics of glycosylphosphatidylinositol (GPI) anchors" @default.
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• W2006194890 doi "https://doi.org/10.1039/c3ob42116c" @default.
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