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- W2006211198 abstract "Design: Community-based cluster-randomised trial. Allocation: Clusters were computer randomised. There were 133 clusters, with a mean population of 4100 people. Blinding: Interventions were not masked. Setting: Rural area of Bangladesh. Patients: All liveborn babies were eligible for enrolment. Of 35 908 eligible infants, 29 760 were enrolled. Over 85% received the intervention within 24 h of birth. Baseline characteristics were similar between the three groups. Intervention: Clusters were randomised to three groups: topical 4% chlorhexidine once at birth, chlorhexidine at birth plus daily cord cleansing with chlorhexidine for 7 days, or dry cord care. Village health workers visited patients daily and applied the chlorhexidine, or provided cord care guidance. Outcomes: Primary outcome was death within 28 days after birth. Cord redness and pus, as assessed by an unblinded health worker, were also analysed. Follow-up period: Outcomes were assessed at days 3, 6, 9, 15 and 28–35. Patient follow-up: An intention-to-treat analysis was performed. Final health status was available for 95% of patients enrolled. Main results Newborns in … Correspondence to Dr David Osrin, Centre for International Health and Development, UCL Institute of Child Health, London, UK; d.osrin{at}ucl.ac.uk" @default.
- W2006211198 created "2016-06-24" @default.
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- W2006211198 date "2012-08-18" @default.
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- W2006211198 title "Application of chlorhexidine to the umbilical cord after birth in low-income settings: two randomised controlled trials" @default.
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- W2006211198 doi "https://doi.org/10.1136/archdischild-2012-302621" @default.
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