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• W2006236491 abstract "The efflux of radiocations (22Na, 2K and 45Ca) and of radiochloride occur as two-stage processes from intact cockroach nerve cords. It is suggested that the initial, fast fraction of efflux comes mainly from the superficial connective tissue layer, the neural lamella, and the clefts between the underlying layer of neuroglia, the perineurium. This is deduced from the lack of effect of a metabolic inhibitor and sodium-transport inhibitors on the fast component of 22Na efflux (which contrast with their effects both on the size an the half-time of the slow component) and from the typically extracellular ratios between the fast components of substantial increase in the fast fractions of 22Na and 45Ca efflux but only a small increase in 36Cl efflux: effects which would be expected if the addition to the fast fraction consisted of ions maintained in Donnan equilibrium with fixed anionic sites within the extracellular system. The presence of such anionic sites is also indicated by lanthanum-binding in the extracellular matrix and by the previous histochemical demonstration of hyaluronic acid in the matrix by Ashhurst and Costin. It is suggested that the anionic glycosaminoglycans provide an extracellular cation reservoir which could serve a role in short-term ionic homeostasis of the brain microenvironment." @default.
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• W2006236491 date "1982-09-01" @default.
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• W2006236491 title "Physiological and ultrastructural evidence for an extracellular anion matrix in the central nervous system of an insect (Periplaneta americana)" @default.
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• W2006236491 doi "https://doi.org/10.1016/0006-8993(82)91250-1" @default.
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