Matches in SemOpenAlex for { <https://semopenalex.org/work/W2006244889> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W2006244889 endingPage "92" @default.
- W2006244889 startingPage "71" @default.
- W2006244889 abstract "With the sensorimotor cortex under continuous irrigation with artificial CSF, 40 electrically silent glial cells ranging in membrain potential from −50 to −95 mV were studied in the outer 400 μm. After penetration of a cell the normal CSF was replaced by a CSF containing 40 mMK+ which flowed until the membrane potential appeared to reach a plateau. The 40mMK+CSF was then replaced by normal CSF, and cell repolarization observed. The response of 10 cells in the outer 30 μm provided an accurate index of glial sensitivity to 40mMK+. Those cells with the highest membrane potential (92mV) showed the greatest depolarization (34mV). Cells with the lowest membrane potential (50 mV) showed the smallest depolarization (12 mV). The depth of 10 of the glial cells was verified by fluorescein electrophoresis and ranged from 10 to 380 μm. The presence of the arachnoid membrane prolonged the time required to obtain equilibration at various cortical depths. Correlation of the electrophysiologic response of these 10 cells with depth revealed the time course of potassium movement through the brain. A cell 10 μm deep reached a plateau in 13 sec while a cell at 380 μm took upwards of 114 sec to approximate a plateau. It is concluded that the magnitude of the response of glial cells to 40 mMK+ is less than what would be predicted by the Nernst equation. The time course of the glial response can be approximated by a diffusion model, corrected for cell and capillary absorption. In addition, the effects of a surface barrier to K+ diffusion have been calculated and discussed." @default.
- W2006244889 created "2016-06-24" @default.
- W2006244889 creator A5015933707 @default.
- W2006244889 creator A5037028051 @default.
- W2006244889 date "1972-03-01" @default.
- W2006244889 modified "2023-10-18" @default.
- W2006244889 title "Response of glia in cat sensorimotor cortex to increased extracellular potassium" @default.
- W2006244889 cites W1844740521 @default.
- W2006244889 cites W1971576248 @default.
- W2006244889 cites W1978329654 @default.
- W2006244889 cites W2003620217 @default.
- W2006244889 cites W2008978687 @default.
- W2006244889 cites W2020506514 @default.
- W2006244889 cites W2034457899 @default.
- W2006244889 cites W2056784171 @default.
- W2006244889 cites W2058698189 @default.
- W2006244889 cites W2060997560 @default.
- W2006244889 cites W2068204303 @default.
- W2006244889 cites W2084659149 @default.
- W2006244889 cites W2089543873 @default.
- W2006244889 cites W2108089336 @default.
- W2006244889 cites W2311237560 @default.
- W2006244889 cites W2322104603 @default.
- W2006244889 cites W2402092330 @default.
- W2006244889 cites W2441506123 @default.
- W2006244889 doi "https://doi.org/10.1016/0006-8993(72)90590-2" @default.
- W2006244889 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/5016004" @default.
- W2006244889 hasPublicationYear "1972" @default.
- W2006244889 type Work @default.
- W2006244889 sameAs 2006244889 @default.
- W2006244889 citedByCount "56" @default.
- W2006244889 crossrefType "journal-article" @default.
- W2006244889 hasAuthorship W2006244889A5015933707 @default.
- W2006244889 hasAuthorship W2006244889A5037028051 @default.
- W2006244889 hasConcept C105702510 @default.
- W2006244889 hasConcept C12554922 @default.
- W2006244889 hasConcept C134018914 @default.
- W2006244889 hasConcept C146403970 @default.
- W2006244889 hasConcept C169760540 @default.
- W2006244889 hasConcept C181911157 @default.
- W2006244889 hasConcept C185263204 @default.
- W2006244889 hasConcept C185592680 @default.
- W2006244889 hasConcept C2780884517 @default.
- W2006244889 hasConcept C2781041448 @default.
- W2006244889 hasConcept C28406088 @default.
- W2006244889 hasConcept C4141045 @default.
- W2006244889 hasConcept C529278444 @default.
- W2006244889 hasConcept C55493867 @default.
- W2006244889 hasConcept C86803240 @default.
- W2006244889 hasConceptScore W2006244889C105702510 @default.
- W2006244889 hasConceptScore W2006244889C12554922 @default.
- W2006244889 hasConceptScore W2006244889C134018914 @default.
- W2006244889 hasConceptScore W2006244889C146403970 @default.
- W2006244889 hasConceptScore W2006244889C169760540 @default.
- W2006244889 hasConceptScore W2006244889C181911157 @default.
- W2006244889 hasConceptScore W2006244889C185263204 @default.
- W2006244889 hasConceptScore W2006244889C185592680 @default.
- W2006244889 hasConceptScore W2006244889C2780884517 @default.
- W2006244889 hasConceptScore W2006244889C2781041448 @default.
- W2006244889 hasConceptScore W2006244889C28406088 @default.
- W2006244889 hasConceptScore W2006244889C4141045 @default.
- W2006244889 hasConceptScore W2006244889C529278444 @default.
- W2006244889 hasConceptScore W2006244889C55493867 @default.
- W2006244889 hasConceptScore W2006244889C86803240 @default.
- W2006244889 hasIssue "1" @default.
- W2006244889 hasLocation W20062448891 @default.
- W2006244889 hasLocation W20062448892 @default.
- W2006244889 hasOpenAccess W2006244889 @default.
- W2006244889 hasPrimaryLocation W20062448891 @default.
- W2006244889 hasRelatedWork W120845308 @default.
- W2006244889 hasRelatedWork W2092465131 @default.
- W2006244889 hasRelatedWork W2137422361 @default.
- W2006244889 hasRelatedWork W2148347482 @default.
- W2006244889 hasRelatedWork W2400752963 @default.
- W2006244889 hasRelatedWork W2406017229 @default.
- W2006244889 hasRelatedWork W2912579268 @default.
- W2006244889 hasRelatedWork W4210938563 @default.
- W2006244889 hasRelatedWork W4243517488 @default.
- W2006244889 hasRelatedWork W4246509532 @default.
- W2006244889 hasVolume "38" @default.
- W2006244889 isParatext "false" @default.
- W2006244889 isRetracted "false" @default.
- W2006244889 magId "2006244889" @default.
- W2006244889 workType "article" @default.