FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2006281337> ?p ?o ?g. }

• W2006281337 endingPage "691" @default.
• W2006281337 startingPage "681" @default.
• W2006281337 abstract "The majority of pharmaceutically relevant drug targets cluster into densely populated target families, thus offering a novel approach that complements the currently favoured screening paradigm in medicinal chemistry. This approach uses a privileged structure concept whereby molecular masterkeys are developed that account for a target family wide structural or functional commonality. Numerous lead compounds, based on multipurpose privileged structures, can be generated that address a variety of targets from a gene family of interest, irrespective of therapeutic area. Several different interpretations of the privileged structure concept will be highlighted, with a strong emphasis on the most stringent application: the optimization of a molecular masterkey for a distinct target family of interest." @default.
• W2006281337 created "2016-06-24" @default.
• W2006281337 creator A5047665746 @default.
• W2006281337 date "2003-08-01" @default.
• W2006281337 modified "2023-10-05" @default.
• W2006281337 title "Medicinal chemistry of target family-directed masterkeys" @default.
• W2006281337 cites W1516151893 @default.
• W2006281337 cites W1967554869 @default.
• W2006281337 cites W1979116564 @default.
• W2006281337 cites W1988248005 @default.
• W2006281337 cites W1991286793 @default.
• W2006281337 cites W1993187658 @default.
• W2006281337 cites W1993488486 @default.
• W2006281337 cites W1995089537 @default.
• W2006281337 cites W2003932717 @default.
• W2006281337 cites W2011647029 @default.
• W2006281337 cites W2014150418 @default.
• W2006281337 cites W2016636882 @default.
• W2006281337 cites W2041464056 @default.
• W2006281337 cites W2041879797 @default.
• W2006281337 cites W2042338355 @default.
• W2006281337 cites W2049640560 @default.
• W2006281337 cites W2057127849 @default.
• W2006281337 cites W2059664977 @default.
• W2006281337 cites W2060335625 @default.
• W2006281337 cites W2060531713 @default.
• W2006281337 cites W2063379654 @default.
• W2006281337 cites W2064222302 @default.
• W2006281337 cites W2067381428 @default.
• W2006281337 cites W2074370114 @default.
• W2006281337 cites W2089486914 @default.
• W2006281337 cites W2109985039 @default.
• W2006281337 cites W2117230055 @default.
• W2006281337 cites W2119708848 @default.
• W2006281337 cites W2127287358 @default.
• W2006281337 cites W2129794631 @default.
• W2006281337 cites W2135732933 @default.
• W2006281337 cites W2153555369 @default.
• W2006281337 cites W2169276524 @default.
• W2006281337 cites W2172057280 @default.
• W2006281337 cites W2318657222 @default.
• W2006281337 cites W2322078746 @default.
• W2006281337 cites W2415990864 @default.
• W2006281337 cites W2915587780 @default.
• W2006281337 doi "https://doi.org/10.1016/s1359-6446(03)02781-8" @default.
• W2006281337 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12927511" @default.
• W2006281337 hasPublicationYear "2003" @default.
• W2006281337 type Work @default.
• W2006281337 sameAs 2006281337 @default.
• W2006281337 citedByCount "203" @default.
• W2006281337 countsByYear W20062813372012 @default.
• W2006281337 countsByYear W20062813372013 @default.
• W2006281337 countsByYear W20062813372014 @default.
• W2006281337 countsByYear W20062813372015 @default.
• W2006281337 countsByYear W20062813372016 @default.
• W2006281337 countsByYear W20062813372017 @default.
• W2006281337 countsByYear W20062813372018 @default.
• W2006281337 countsByYear W20062813372019 @default.
• W2006281337 countsByYear W20062813372020 @default.
• W2006281337 countsByYear W20062813372021 @default.
• W2006281337 countsByYear W20062813372022 @default.
• W2006281337 countsByYear W20062813372023 @default.
• W2006281337 crossrefType "journal-article" @default.
• W2006281337 hasAuthorship W2006281337A5047665746 @default.
• W2006281337 hasConcept C136197465 @default.
• W2006281337 hasConcept C154945302 @default.
• W2006281337 hasConcept C171250308 @default.
• W2006281337 hasConcept C185592680 @default.
• W2006281337 hasConcept C192562407 @default.
• W2006281337 hasConcept C2989108626 @default.
• W2006281337 hasConcept C41008148 @default.
• W2006281337 hasConcept C55493867 @default.
• W2006281337 hasConcept C60644358 @default.
• W2006281337 hasConcept C70721500 @default.
• W2006281337 hasConcept C74187038 @default.
• W2006281337 hasConcept C86803240 @default.
• W2006281337 hasConceptScore W2006281337C136197465 @default.
• W2006281337 hasConceptScore W2006281337C154945302 @default.
• W2006281337 hasConceptScore W2006281337C171250308 @default.
• W2006281337 hasConceptScore W2006281337C185592680 @default.
• W2006281337 hasConceptScore W2006281337C192562407 @default.
• W2006281337 hasConceptScore W2006281337C2989108626 @default.
• W2006281337 hasConceptScore W2006281337C41008148 @default.
• W2006281337 hasConceptScore W2006281337C55493867 @default.
• W2006281337 hasConceptScore W2006281337C60644358 @default.
• W2006281337 hasConceptScore W2006281337C70721500 @default.
• W2006281337 hasConceptScore W2006281337C74187038 @default.
• W2006281337 hasConceptScore W2006281337C86803240 @default.
• W2006281337 hasIssue "15" @default.
• W2006281337 hasLocation W20062813371 @default.
• W2006281337 hasLocation W20062813372 @default.
• W2006281337 hasOpenAccess W2006281337 @default.
• W2006281337 hasPrimaryLocation W20062813371 @default.
• W2006281337 hasRelatedWork W1970275325 @default.
• W2006281337 hasRelatedWork W2001717001 @default.
• W2006281337 hasRelatedWork W2009484275 @default.
• W2006281337 hasRelatedWork W2108103746 @default.
• W2006281337 hasRelatedWork W2119629574 @default.

• next