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- W2006291628 abstract "Aerobic exercise capacity (peak VO2) and an active life style are related to long-term survival and to a reduction in cardiovascular morbidity in subjects with cardiovascular disease. However, the majority of cardiac patients do not engage enough in physical activity to obtain or maintain the benefits of a physically active lifestyle. There is a need for innovative rehabilitation methods aiming at increasing longer-term adherence and hence more sustained effects on physical fitness. One strategy might be the use of home-based training in combination with telemonitoring guidance. Here we describe the rationale, design and methods of the Tele-Rehabilitation in Coronary Heart disease study (TRiCH). The main objective of TRiCH is to compare the longer-term (=1 year) effects of a 3-month patient-tailored homebased cardiac rehabilitation program with telemonitoring guidance (Home-CR) with a supervised center-based cardiac rehabilitation program (Center-CR) in coronary artery disease patients (phase III). The study is planned as a randomized controlled prospective trial that will randomize 105 coronary artery disease patients (40-75 yrs) who have successfully completed a three month ambulatory cardiac rehabilitation program (phase II) to one of the three groups: Home-CR, Center-CR or a control group on a 1:1:1 basis. The exercise programs (frequency, intensity and time of exercise) of patients randomized to Home-CR or Center-CR will be designed according to current exercise recommendations. Patients in the control group will receive the advice to maintain a physically active lifestyle. Assessments will be performed at baseline, after 12 weeks of intervention and at one year of follow-up. The primary outcome measure is change in exercise capacity assessed by peak oxygen uptake at 3 and 12 months of follow-up. Secondary outcomes include determinants of exercise capacity, i.e. physical activity, endothelial function and muscle function, as well astraditional cardiovascular risk factors and quality of life. It is hypothesized that home-based training with telemonitoring guidance will result in higher levels of peak VO2 at one year of follow-up. Enrollment started in February 2014; last enrollment is expected in November 2015." @default.
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- W2006291628 date "2014-01-01" @default.
- W2006291628 modified "2023-09-27" @default.
- W2006291628 title "A Randomized Controlled Study Comparing Home-Based Training with Telemonitoring Guidance Versus Center-Based Training in Patients with Coronary Heart Disease: Rationale and Design of the Tele-Rehabilitation in Coronary Heart Disease (TRiCH) Study" @default.
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- W2006291628 doi "https://doi.org/10.4172/2167-0870.1000175" @default.
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