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- W2006334471 abstract "Exposure of mice to a 120 dB SPL broad band click sound for 3 h per day induced expression of hypoxia-inducible factor-1α (HIF-1α) in the organ of Corti, lateral wall tissue and spiral ganglion cells. In the organ of Corti, HIF-1α was expressed in inner and outer hair cells, pillar cells and Deiters' cells, but not in Hensen's cells or the tectorial, Reissner's or basement membrane. HIF-1α expression was definitely increased in mice with a permanent threshold shift, where the hearing level did not recover, even after 4 weeks. These results suggest that noise may induce tissue hypoxia in the inner ear and that the further study on the role of HIF-1α will be needed." @default.
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- W2006334471 date "2004-10-01" @default.
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- W2006334471 title "Accumulation of hypoxia-inducible factor-1α in mouse inner ear by noise stimulation" @default.
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- W2006334471 doi "https://doi.org/10.1097/00001756-200410250-00010" @default.
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