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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2006341454> ?p ?o ?g. }

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• W2006341454 abstract "Cross-sectional studies have suggested that infection with human immunodeficiency virus (HIV) type 1 could reduce the mitochondrial DNA (mtDNA) content of blood cells. We investigated mtDNA content in peripheral blood mononuclear cells (PBMCs) obtained from 36 antiretroviral therapy-naive documented HIV-1 seroconverters, before and after seroconversion. mtDNA content statistically significantly decreased 1 year after seroconversion and showed a nonsignificant decrease during the subsequent 4 years. These findings confirm that infection with HIV-1 may, itself, reduce mtDNA content, at least within PBMCs. This could have implications for the subsequent development of mitochondrial toxicities associated with the use of nucleoside analogue reverse-transcriptase inhibitors." @default.
• W2006341454 created "2016-06-24" @default.
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• W2006341454 date "2005-05-01" @default.
• W2006341454 modified "2023-09-27" @default.
• W2006341454 title "Infection with HIV‐1 Induces a Decrease in mtDNA" @default.
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• W2006341454 doi "https://doi.org/10.1086/429412" @default.
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