Matches in SemOpenAlex for { <https://semopenalex.org/work/W2006346064> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2006346064 endingPage "243" @default.
- W2006346064 startingPage "237" @default.
- W2006346064 abstract "To determine the pathogenicities of mutated mtDNAs in patients with respiration defects, the possible involvement of nuclear DNA mutations has to be excluded, since respiratory function is controlled by both nuclear DNA and mtDNA. This was achieved by showing that the mutated mtDNAs and respiration defects were co-transferred from patients to mtDNA-less human cells, and the resultant cybrid clones carrying mutated mtDNAs expressed respiration defects. To decide whether the cybrid clones expressed respiration defects, in this study the lowest limits of normal respiratory function were evaluated by transfer of mtDNAs from 54 normal subjects to mtDNA-less HeLa cells. The resultant cybrid clones showed that 71% respiratory function was the lowest limit of mtDNAs from normal subjects. On the other hand, cybrid clones carrying pathogenic mtDNAs from patients with mitochondrial diseases showed 0–64% respiratory function, suggesting that less than 71% respiratory function in cybrid clones should be a reliable indicator of whether the mutated mtDNAs of the patients were pathogenic." @default.
- W2006346064 created "2016-06-24" @default.
- W2006346064 creator A5004010691 @default.
- W2006346064 creator A5018316993 @default.
- W2006346064 creator A5024043624 @default.
- W2006346064 creator A5033614902 @default.
- W2006346064 creator A5041403109 @default.
- W2006346064 creator A5044260239 @default.
- W2006346064 creator A5063810474 @default.
- W2006346064 creator A5071366565 @default.
- W2006346064 creator A5081800520 @default.
- W2006346064 creator A5087985088 @default.
- W2006346064 date "2004-02-01" @default.
- W2006346064 modified "2023-10-18" @default.
- W2006346064 title "Determination of Normal Ranges of Mitochondrial Respiratory Activities by mtDNA Transfer from 54 Human Subjects to mtDNA-less HeLa Cells for Identification of the Pathogenicities of Mutated mtDNAs" @default.
- W2006346064 cites W1554250492 @default.
- W2006346064 cites W1940308554 @default.
- W2006346064 cites W1972140717 @default.
- W2006346064 cites W1979279686 @default.
- W2006346064 cites W2012102114 @default.
- W2006346064 cites W2032115850 @default.
- W2006346064 cites W2032118993 @default.
- W2006346064 cites W2066250257 @default.
- W2006346064 cites W2068233666 @default.
- W2006346064 cites W2068568687 @default.
- W2006346064 cites W2092505879 @default.
- W2006346064 cites W2109291482 @default.
- W2006346064 cites W2114101869 @default.
- W2006346064 cites W2116256186 @default.
- W2006346064 cites W2120792422 @default.
- W2006346064 cites W2129740452 @default.
- W2006346064 cites W2133140331 @default.
- W2006346064 cites W2162288115 @default.
- W2006346064 cites W4244588350 @default.
- W2006346064 doi "https://doi.org/10.1093/jb/mvh028" @default.
- W2006346064 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15047726" @default.
- W2006346064 hasPublicationYear "2004" @default.
- W2006346064 type Work @default.
- W2006346064 sameAs 2006346064 @default.
- W2006346064 citedByCount "4" @default.
- W2006346064 crossrefType "journal-article" @default.
- W2006346064 hasAuthorship W2006346064A5004010691 @default.
- W2006346064 hasAuthorship W2006346064A5018316993 @default.
- W2006346064 hasAuthorship W2006346064A5024043624 @default.
- W2006346064 hasAuthorship W2006346064A5033614902 @default.
- W2006346064 hasAuthorship W2006346064A5041403109 @default.
- W2006346064 hasAuthorship W2006346064A5044260239 @default.
- W2006346064 hasAuthorship W2006346064A5063810474 @default.
- W2006346064 hasAuthorship W2006346064A5071366565 @default.
- W2006346064 hasAuthorship W2006346064A5081800520 @default.
- W2006346064 hasAuthorship W2006346064A5087985088 @default.
- W2006346064 hasConcept C104317684 @default.
- W2006346064 hasConcept C105702510 @default.
- W2006346064 hasConcept C153911025 @default.
- W2006346064 hasConcept C182215343 @default.
- W2006346064 hasConcept C24586158 @default.
- W2006346064 hasConcept C2777366897 @default.
- W2006346064 hasConcept C28859421 @default.
- W2006346064 hasConcept C3020377403 @default.
- W2006346064 hasConcept C501734568 @default.
- W2006346064 hasConcept C534529494 @default.
- W2006346064 hasConcept C54355233 @default.
- W2006346064 hasConcept C81885089 @default.
- W2006346064 hasConcept C86803240 @default.
- W2006346064 hasConceptScore W2006346064C104317684 @default.
- W2006346064 hasConceptScore W2006346064C105702510 @default.
- W2006346064 hasConceptScore W2006346064C153911025 @default.
- W2006346064 hasConceptScore W2006346064C182215343 @default.
- W2006346064 hasConceptScore W2006346064C24586158 @default.
- W2006346064 hasConceptScore W2006346064C2777366897 @default.
- W2006346064 hasConceptScore W2006346064C28859421 @default.
- W2006346064 hasConceptScore W2006346064C3020377403 @default.
- W2006346064 hasConceptScore W2006346064C501734568 @default.
- W2006346064 hasConceptScore W2006346064C534529494 @default.
- W2006346064 hasConceptScore W2006346064C54355233 @default.
- W2006346064 hasConceptScore W2006346064C81885089 @default.
- W2006346064 hasConceptScore W2006346064C86803240 @default.
- W2006346064 hasIssue "2" @default.
- W2006346064 hasLocation W20063460641 @default.
- W2006346064 hasLocation W20063460642 @default.
- W2006346064 hasOpenAccess W2006346064 @default.
- W2006346064 hasPrimaryLocation W20063460641 @default.
- W2006346064 hasRelatedWork W1534219729 @default.
- W2006346064 hasRelatedWork W2000696562 @default.
- W2006346064 hasRelatedWork W2023783781 @default.
- W2006346064 hasRelatedWork W2061946546 @default.
- W2006346064 hasRelatedWork W2070231746 @default.
- W2006346064 hasRelatedWork W2095005453 @default.
- W2006346064 hasRelatedWork W2329573718 @default.
- W2006346064 hasRelatedWork W2412623779 @default.
- W2006346064 hasRelatedWork W2804848391 @default.
- W2006346064 hasRelatedWork W4281938843 @default.
- W2006346064 hasVolume "135" @default.
- W2006346064 isParatext "false" @default.
- W2006346064 isRetracted "false" @default.
- W2006346064 magId "2006346064" @default.
- W2006346064 workType "article" @default.