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- W2006346522 abstract "MBL (mannose-binding lectin) is a pattern recognition molecule and a component of innate immunity, the first line of the host defence system against foreign bodies and pathogens. MBL deficiency is common in humans and has been associated with immunodeficiency. We have generated mouse models of MBL deficiency in order to explore the molecular mechanisms of MBL function in disease and health. In addition to confirming findings from human clinical research, these model studies have uncovered unexpected roles of MBL and evidence of its interaction with other molecules of the innate immune system." @default.
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- W2006346522 date "2008-11-19" @default.
- W2006346522 modified "2023-09-23" @default.
- W2006346522 title "Lessons learned from murine models of mannose-binding lectin deficiency" @default.
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- W2006346522 doi "https://doi.org/10.1042/bst0361487" @default.
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