FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2006349275> ?p ?o ?g. }

• W2006349275 endingPage "264" @default.
• W2006349275 startingPage "264" @default.
• W2006349275 abstract "purpose. To study tear trypsin inhibitory capacity (T-TIC), serum trypsin inhibitory capacity (S-TIC) and their relationship to matrix metalloproteinases (MMP)-1 and -9 in patients with vernal keratoconjunctivitis (VKC). methods. In the first phase of the study, inactivation of α-1 antitrypsin (AAT) by MMP-1 and -9 was investigated in vitro. Subsequently, tear samples were collected after clinical evaluation from 14 patients with active VKC and 15 normal control subjects. Tear cytology was performed on all samples. Levels of T-TIC and S-TIC were determined by spectrophotometry, whereas levels of tear pro-MMP-1, pro-MMP-9, and active MMP-1 and -9 were determined by enzyme-linked immunosorbent assay (ELISA). results. MMP-1 and -9 inactivated AAT in vitro. S-TIC was significantly higher (P < 0.0001), and T-TIC (P < 0.0001) significantly lower in VKC samples. Tear levels of pro-MMP-1 and pro-MMP-9, and the activity of MMP-1 and -9 was significantly greater in patients with VKC than in healthy subjects (P < 0.0001). There was no significant correlation between T-TIC, MMP-1, and MMP-9 activity. In addition, T-TIC was not correlated to the total clinical score or to single clinical sign scores. conclusions. In this study, tear trypsin inhibitory capacity was shown to be reduced and tear MMP-1 and -9 activity increased in patients with VKC. Although T-TIC did not correlate with VKC severity, a local reduced inhibitory capacity of ATT may facilitate or prolong conjunctival inflammation in VKC." @default.
• W2006349275 created "2016-06-24" @default.
• W2006349275 creator A5035478404 @default.
• W2006349275 creator A5044713800 @default.
• W2006349275 creator A5059244618 @default.
• W2006349275 creator A5083904106 @default.
• W2006349275 creator A5087248134 @default.
• W2006349275 creator A5087368272 @default.
• W2006349275 date "2007-01-01" @default.
• W2006349275 modified "2023-10-16" @default.
• W2006349275 title "Trypsin Inhibitory Capacity in Vernal Keratoconjunctivitis" @default.
• W2006349275 cites W1493993231 @default.
• W2006349275 cites W1504163891 @default.
• W2006349275 cites W1539133960 @default.
• W2006349275 cites W1539736798 @default.
• W2006349275 cites W1572914688 @default.
• W2006349275 cites W1642011778 @default.
• W2006349275 cites W1864210773 @default.
• W2006349275 cites W1886491539 @default.
• W2006349275 cites W1892106876 @default.
• W2006349275 cites W1917053440 @default.
• W2006349275 cites W1962783620 @default.
• W2006349275 cites W1964635647 @default.
• W2006349275 cites W1965088983 @default.
• W2006349275 cites W1967158543 @default.
• W2006349275 cites W1969332102 @default.
• W2006349275 cites W1970787143 @default.
• W2006349275 cites W1972369437 @default.
• W2006349275 cites W1972556193 @default.
• W2006349275 cites W1974938997 @default.
• W2006349275 cites W1986427883 @default.
• W2006349275 cites W1987298403 @default.
• W2006349275 cites W1991822962 @default.
• W2006349275 cites W1994897036 @default.
• W2006349275 cites W2005415233 @default.
• W2006349275 cites W2007855338 @default.
• W2006349275 cites W2014557893 @default.
• W2006349275 cites W2016419966 @default.
• W2006349275 cites W2016801684 @default.
• W2006349275 cites W2020553724 @default.
• W2006349275 cites W2026617189 @default.
• W2006349275 cites W2033124365 @default.
• W2006349275 cites W2037116841 @default.
• W2006349275 cites W2041984351 @default.
• W2006349275 cites W2044904349 @default.
• W2006349275 cites W2057099776 @default.
• W2006349275 cites W2057728707 @default.
• W2006349275 cites W2068025041 @default.
• W2006349275 cites W2076170762 @default.
• W2006349275 cites W2082737488 @default.
• W2006349275 cites W2089486619 @default.
• W2006349275 cites W2091312903 @default.
• W2006349275 cites W2092641596 @default.
• W2006349275 cites W2107873069 @default.
• W2006349275 cites W2109658199 @default.
• W2006349275 cites W2120959864 @default.
• W2006349275 cites W2121177003 @default.
• W2006349275 cites W2143658570 @default.
• W2006349275 cites W2155326631 @default.
• W2006349275 cites W2164484272 @default.
• W2006349275 cites W2414844379 @default.
• W2006349275 cites W330357786 @default.
• W2006349275 doi "https://doi.org/10.1167/iovs.06-0758" @default.
• W2006349275 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17197542" @default.
• W2006349275 hasPublicationYear "2007" @default.
• W2006349275 type Work @default.
• W2006349275 sameAs 2006349275 @default.
• W2006349275 citedByCount "17" @default.
• W2006349275 countsByYear W20063492752013 @default.
• W2006349275 countsByYear W20063492752014 @default.
• W2006349275 countsByYear W20063492752018 @default.
• W2006349275 countsByYear W20063492752019 @default.
• W2006349275 countsByYear W20063492752020 @default.
• W2006349275 crossrefType "journal-article" @default.
• W2006349275 hasAuthorship W2006349275A5035478404 @default.
• W2006349275 hasAuthorship W2006349275A5044713800 @default.
• W2006349275 hasAuthorship W2006349275A5059244618 @default.
• W2006349275 hasAuthorship W2006349275A5083904106 @default.
• W2006349275 hasAuthorship W2006349275A5087248134 @default.
• W2006349275 hasAuthorship W2006349275A5087368272 @default.
• W2006349275 hasBestOaLocation W20063492751 @default.
• W2006349275 hasConcept C109523444 @default.
• W2006349275 hasConcept C126322002 @default.
• W2006349275 hasConcept C16005928 @default.
• W2006349275 hasConcept C181199279 @default.
• W2006349275 hasConcept C185592680 @default.
• W2006349275 hasConcept C203014093 @default.
• W2006349275 hasConcept C2776469317 @default.
• W2006349275 hasConcept C2778064476 @default.
• W2006349275 hasConcept C2780340462 @default.
• W2006349275 hasConcept C55493867 @default.
• W2006349275 hasConcept C71924100 @default.
• W2006349275 hasConcept C90924648 @default.
• W2006349275 hasConceptScore W2006349275C109523444 @default.
• W2006349275 hasConceptScore W2006349275C126322002 @default.
• W2006349275 hasConceptScore W2006349275C16005928 @default.
• W2006349275 hasConceptScore W2006349275C181199279 @default.
• W2006349275 hasConceptScore W2006349275C185592680 @default.

• next