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- W2006360074 abstract "Purpose of review The ability of cells to adhere to other cells and extracellular matrix (ECM) through cellular adhesion molecules (CAMs) is central to tissue remodeling and inflammation. This review discusses the potential role of CAMs in development of synovial inflammation through regulating the recruitment of inflammatory cells via endothelial–leukocyte interactions, the organization and activation of leukocytes in the synovial sublining, and the formation and behavior of the hyperplastic synovial lining. Recent findings Over the past several years valuable insight has been gained into the role of cell–cell and cell–ECM adhesive interactions in synovial organization and inflammation. Recently, cadherin-11 was identified on fibroblast-like synoviocytes and has been demonstrated to play a central role in synovial lining organization. Furthermore, studies using animal models of inflammatory arthritis have demonstrated critical roles for E- and P-selectins, CD11a/CD18 [lymphocyte function-associated antigen (LFA)-1], α4β1 integrin, and cadherin-11 in the development of synovial inflammation. Summary Cell–cell and cell–ECM interactions through CAMs play an important role in synovial inflammation. Future studies of CAMs are needed to define more thoroughly their role in synovial inflammation and their potential as therapeutic targets in the treatment of rheumatoid arthritis and related inflammatory arthritic conditions." @default.
- W2006360074 created "2016-06-24" @default.
- W2006360074 creator A5000815014 @default.
- W2006360074 creator A5002778799 @default.
- W2006360074 date "2006-05-01" @default.
- W2006360074 modified "2023-10-12" @default.
- W2006360074 title "Role of adhesion molecules in synovial inflammation" @default.
- W2006360074 cites W1484020898 @default.
- W2006360074 cites W1486222787 @default.
- W2006360074 cites W1532717000 @default.
- W2006360074 cites W1533598723 @default.
- W2006360074 cites W1558826269 @default.
- W2006360074 cites W1562441478 @default.
- W2006360074 cites W1576773659 @default.
- W2006360074 cites W1588921208 @default.
- W2006360074 cites W1590814315 @default.
- W2006360074 cites W1591479203 @default.
- W2006360074 cites W1754450320 @default.
- W2006360074 cites W1841539097 @default.
- W2006360074 cites W1922855985 @default.
- W2006360074 cites W1970063119 @default.
- W2006360074 cites W1970547229 @default.
- W2006360074 cites W1975041769 @default.
- W2006360074 cites W1979080480 @default.
- W2006360074 cites W1988626998 @default.
- W2006360074 cites W1992587170 @default.
- W2006360074 cites W2006288082 @default.
- W2006360074 cites W2009074857 @default.
- W2006360074 cites W2011856674 @default.
- W2006360074 cites W2018109254 @default.
- W2006360074 cites W2021802559 @default.
- W2006360074 cites W2022234757 @default.
- W2006360074 cites W2027724598 @default.
- W2006360074 cites W2031092466 @default.
- W2006360074 cites W2034585843 @default.
- W2006360074 cites W2035553802 @default.
- W2006360074 cites W2037632429 @default.
- W2006360074 cites W2039522938 @default.
- W2006360074 cites W2041495478 @default.
- W2006360074 cites W2046972996 @default.
- W2006360074 cites W2051186133 @default.
- W2006360074 cites W2061974386 @default.
- W2006360074 cites W2062058886 @default.
- W2006360074 cites W2063220206 @default.
- W2006360074 cites W2064057557 @default.
- W2006360074 cites W2068272711 @default.
- W2006360074 cites W2072286439 @default.
- W2006360074 cites W2072311402 @default.
- W2006360074 cites W2072647934 @default.
- W2006360074 cites W2077563248 @default.
- W2006360074 cites W2081972139 @default.
- W2006360074 cites W2082952854 @default.
- W2006360074 cites W2083172750 @default.
- W2006360074 cites W2084885576 @default.
- W2006360074 cites W2099675490 @default.
- W2006360074 cites W2100208042 @default.
- W2006360074 cites W2102411854 @default.
- W2006360074 cites W2102598791 @default.
- W2006360074 cites W2104218413 @default.
- W2006360074 cites W2105367923 @default.
- W2006360074 cites W2106467284 @default.
- W2006360074 cites W2107845315 @default.
- W2006360074 cites W2110129355 @default.
- W2006360074 cites W2110243379 @default.
- W2006360074 cites W2111944995 @default.
- W2006360074 cites W2117624154 @default.
- W2006360074 cites W2128322342 @default.
- W2006360074 cites W2131093613 @default.
- W2006360074 cites W2140437708 @default.
- W2006360074 cites W2143183772 @default.
- W2006360074 cites W2143759076 @default.
- W2006360074 cites W2150670685 @default.
- W2006360074 cites W2153039655 @default.
- W2006360074 cites W2156285494 @default.
- W2006360074 cites W2156676347 @default.
- W2006360074 cites W2162766966 @default.
- W2006360074 cites W2169563230 @default.
- W2006360074 cites W2170317819 @default.
- W2006360074 cites W2171623013 @default.
- W2006360074 cites W2328126238 @default.
- W2006360074 cites W2402721517 @default.
- W2006360074 cites W254705465 @default.
- W2006360074 cites W4361865601 @default.
- W2006360074 doi "https://doi.org/10.1097/01.bor.0000218948.42730.39" @default.
- W2006360074 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16582691" @default.
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