Matches in SemOpenAlex for { <https://semopenalex.org/work/W2006364027> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W2006364027 endingPage "337" @default.
- W2006364027 startingPage "321" @default.
- W2006364027 abstract "Rats have been dosed repeatedly with 1.08 mg/kg of HgCl2 for up to 70 days and studied ultrastructurally. After two weeks, focal areas of disruption of endoplasmic reticulum (ER) occur in the neurons of the spinal ganglia; other features are present that are found also in methyl mercury intoxication in this species. At 1 month and longer on this dosing schedule a constant finding is loss of ribosomes from the rough ER of some neurons which persisted throughout the study. Occasional axon degeneration was found in the sciatic nerves of those animals having received the largest doses of HgCl2. Alterations in vascular endothelial cells and enlargement and other abnormalities in mitochondria of the neurones of spinal ganglia were also found. Because of similarities in the ultrastructural changes in the early phases of methyl mercury intoxication and those in chronic HgCl2 intoxication, it is suggested that degraded inorganic mercury may be important in the pathogenesis of the intracellular disturbances in methyl mercury poisoning. It is suggested that the excessive neurotoxicity of methyl mercury compounds may reside in the lipid solubility of these compounds and hence their ready capacity to enter cells." @default.
- W2006364027 created "2016-06-24" @default.
- W2006364027 creator A5026174405 @default.
- W2006364027 creator A5032745836 @default.
- W2006364027 creator A5075409476 @default.
- W2006364027 date "1975-10-01" @default.
- W2006364027 modified "2023-10-04" @default.
- W2006364027 title "THE EFFECT OF CHRONIC DOSING WITH MERCURIC CHLORIDE ON DORSAL ROOT AND TRIGEMINAL GANGLIA OF RATS" @default.
- W2006364027 cites W1044978559 @default.
- W2006364027 cites W142080826 @default.
- W2006364027 cites W2003655092 @default.
- W2006364027 cites W2009016920 @default.
- W2006364027 cites W2032199944 @default.
- W2006364027 cites W2056023787 @default.
- W2006364027 cites W2064075500 @default.
- W2006364027 cites W2085799500 @default.
- W2006364027 cites W2150788932 @default.
- W2006364027 cites W2246367234 @default.
- W2006364027 cites W2758871505 @default.
- W2006364027 cites W2885471072 @default.
- W2006364027 cites W4233659679 @default.
- W2006364027 cites W995962601 @default.
- W2006364027 doi "https://doi.org/10.1111/j.1365-2990.1975.tb00656.x" @default.
- W2006364027 hasPublicationYear "1975" @default.
- W2006364027 type Work @default.
- W2006364027 sameAs 2006364027 @default.
- W2006364027 citedByCount "25" @default.
- W2006364027 crossrefType "journal-article" @default.
- W2006364027 hasAuthorship W2006364027A5026174405 @default.
- W2006364027 hasAuthorship W2006364027A5032745836 @default.
- W2006364027 hasAuthorship W2006364027A5075409476 @default.
- W2006364027 hasConcept C105702510 @default.
- W2006364027 hasConcept C126322002 @default.
- W2006364027 hasConcept C142724271 @default.
- W2006364027 hasConcept C158617107 @default.
- W2006364027 hasConcept C185592680 @default.
- W2006364027 hasConcept C199360897 @default.
- W2006364027 hasConcept C2777777548 @default.
- W2006364027 hasConcept C2778234491 @default.
- W2006364027 hasConcept C2779491297 @default.
- W2006364027 hasConcept C2779530196 @default.
- W2006364027 hasConcept C2780942790 @default.
- W2006364027 hasConcept C2781149210 @default.
- W2006364027 hasConcept C29730261 @default.
- W2006364027 hasConcept C41008148 @default.
- W2006364027 hasConcept C55493867 @default.
- W2006364027 hasConcept C71924100 @default.
- W2006364027 hasConcept C86803240 @default.
- W2006364027 hasConcept C87555872 @default.
- W2006364027 hasConceptScore W2006364027C105702510 @default.
- W2006364027 hasConceptScore W2006364027C126322002 @default.
- W2006364027 hasConceptScore W2006364027C142724271 @default.
- W2006364027 hasConceptScore W2006364027C158617107 @default.
- W2006364027 hasConceptScore W2006364027C185592680 @default.
- W2006364027 hasConceptScore W2006364027C199360897 @default.
- W2006364027 hasConceptScore W2006364027C2777777548 @default.
- W2006364027 hasConceptScore W2006364027C2778234491 @default.
- W2006364027 hasConceptScore W2006364027C2779491297 @default.
- W2006364027 hasConceptScore W2006364027C2779530196 @default.
- W2006364027 hasConceptScore W2006364027C2780942790 @default.
- W2006364027 hasConceptScore W2006364027C2781149210 @default.
- W2006364027 hasConceptScore W2006364027C29730261 @default.
- W2006364027 hasConceptScore W2006364027C41008148 @default.
- W2006364027 hasConceptScore W2006364027C55493867 @default.
- W2006364027 hasConceptScore W2006364027C71924100 @default.
- W2006364027 hasConceptScore W2006364027C86803240 @default.
- W2006364027 hasConceptScore W2006364027C87555872 @default.
- W2006364027 hasIssue "4" @default.
- W2006364027 hasLocation W20063640271 @default.
- W2006364027 hasOpenAccess W2006364027 @default.
- W2006364027 hasPrimaryLocation W20063640271 @default.
- W2006364027 hasRelatedWork W127623931 @default.
- W2006364027 hasRelatedWork W1985278942 @default.
- W2006364027 hasRelatedWork W2021603613 @default.
- W2006364027 hasRelatedWork W2044978599 @default.
- W2006364027 hasRelatedWork W2158188835 @default.
- W2006364027 hasRelatedWork W2396704575 @default.
- W2006364027 hasRelatedWork W2748952813 @default.
- W2006364027 hasRelatedWork W2899084033 @default.
- W2006364027 hasRelatedWork W3030031134 @default.
- W2006364027 hasRelatedWork W606730757 @default.
- W2006364027 hasVolume "1" @default.
- W2006364027 isParatext "false" @default.
- W2006364027 isRetracted "false" @default.
- W2006364027 magId "2006364027" @default.
- W2006364027 workType "article" @default.