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- W2006376277 abstract "Study Objective: Our aim was to report two individual case reports on the rarely occurring and lifethreatening condition of ectopic pregnancy developing in a Caesarean section scar and a cervical ectopic pregnancy in the second trimester. Conclusion: Intramuscular methotrexate is still a good option for extratubarian ectopic pregnancies. Due the rareness of these cases further studies are necessaries to determinate the safeties of the use of methotrexate. Design: Case report. Setting: Communitary teaching hospital. Patients: Case 1: a 27 year old primigravida with a second trimester cervical ectopic pregnancy. Case 2: a 35 year old gravida 4 with history of 3 previous cesarean deliveries. Intervention: The patient in case 1 presented to our emergency room with vaginal bleeding, finding a cervical ectopic pregnancy at 14 weeks, treated with intramuscular methotrexate, uterine artery embolization and finally curettage removing the remaining tissue with no massive bleeding. The second case is a patient with a first trimester heterotopic cesarean scar pregnancy. The patient decided to terminate the pregnancy and intramuscular methotrexate was given up to 3 doses and further follow up showed a total resolution of the ectopic pregnancy. Measurements and Main Results: Serum concentrations of the B-human chorionic gonadotropin were monitored until negative values. In the case number one despite the negative serum concentration of the homone, the patient had a remanent tissue that was removed during the curettage. Both patients did not present any side effects related to the methotrexate, no blood transfussion was required also in any of the patients. Conclusion: Intramuscular methotrexate is still a good option for extratubarian ectopic pregnancies. Due the rareness of these cases further studies are necessaries to determinate the safeties of the use of methotrexate." @default.
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- W2006376277 date "2010-11-01" @default.
- W2006376277 modified "2023-09-26" @default.
- W2006376277 title "Is Still Methotrexate an Option for Extratubarian Ectopic Pregnancies?" @default.
- W2006376277 doi "https://doi.org/10.1016/j.jmig.2010.08.084" @default.
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