FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2006377941> ?p ?o ?g. }

• W2006377941 endingPage "527" @default.
• W2006377941 startingPage "521" @default.
• W2006377941 abstract "Background : One of the important proangiogenic factors involved in the growth of normal and neoplastic tissues is vascular endothelial growth factor (VEGF). Aim : We hypothesized that serum VEGF concentration would differ between patients with metastatic and non-metastatic thyroid cancer, multinodular goiter, and healthy subjects. We also hypothesized that endogenous TSH stimulation would affect serum VEGF level. Subjects and methods : The study group consisted of 71 patients (62 females and 9 males), aged 44.9 ± 12.3 years, with differentiated thyroid cancer (50 papillary, 17 follicular, and 4 oxyphilic), treated in our department during the years 2003–2006. All patients had undergone total or near-total thyroidectomy and radioactive iodine treatment, that had resulted in remission in 59 patients and persistent/recurrent disease in 12 patients. The study included two control groups: 30 patients with nontoxic multinodular goiter and 30 healthy subjects. Results : Serum VEGF concentrations were significantly higher in patients with distant metastases than those in remission or healthy patients. (423.4 vs 217.6 vs 235.55 pg/ml respectively, P < 0.05). This was not observed in patients with locoregional metastases. During endogenous TSH stimulation, VEGF decreased significantly (215.3 vs 169.6 pg/ml, P < 0.05). Patients with multinodular goiter showed significantly lower VEGF concentrations than the remaining study groups. Conclusions : Serum VEGF concentration might be used as an additional marker of thyroid cancer with distant metastases, but its interpretation should be undertaken very cautiously. Endogenous TSH stimulation decreases VEGF levels in patients either with or without thyroid tissue, suggesting that its regulatory effects are through receptors located outside the thyrocytes." @default.
• W2006377941 created "2016-06-24" @default.
• W2006377941 creator A5002814926 @default.
• W2006377941 creator A5031402469 @default.
• W2006377941 creator A5076354360 @default.
• W2006377941 creator A5080872207 @default.
• W2006377941 creator A5089542434 @default.
• W2006377941 date "2007-10-01" @default.
• W2006377941 modified "2023-10-09" @default.
• W2006377941 title "The comparison of serum vascular endothelial growth factor levels between patients with metastatic and non-metastatic thyroid cancer, and patients with nontoxic multinodular goiter" @default.
• W2006377941 cites W1968088171 @default.
• W2006377941 cites W1978404812 @default.
• W2006377941 cites W1978516786 @default.
• W2006377941 cites W1982060502 @default.
• W2006377941 cites W1982618742 @default.
• W2006377941 cites W1985705527 @default.
• W2006377941 cites W1988116788 @default.
• W2006377941 cites W2000073587 @default.
• W2006377941 cites W2018822308 @default.
• W2006377941 cites W2039073756 @default.
• W2006377941 cites W2042578565 @default.
• W2006377941 cites W2045579423 @default.
• W2006377941 cites W2051300916 @default.
• W2006377941 cites W2056649371 @default.
• W2006377941 cites W2067161404 @default.
• W2006377941 cites W2077129920 @default.
• W2006377941 cites W2083005649 @default.
• W2006377941 cites W2087491949 @default.
• W2006377941 cites W2089327677 @default.
• W2006377941 cites W2101642991 @default.
• W2006377941 cites W2112892701 @default.
• W2006377941 cites W2113940512 @default.
• W2006377941 cites W2115615859 @default.
• W2006377941 cites W2125153669 @default.
• W2006377941 cites W2127339144 @default.
• W2006377941 cites W2151747343 @default.
• W2006377941 cites W2154944395 @default.
• W2006377941 cites W2159196526 @default.
• W2006377941 cites W2163085731 @default.
• W2006377941 cites W2163384356 @default.
• W2006377941 cites W2169792450 @default.
• W2006377941 cites W2401614631 @default.
• W2006377941 cites W2439530292 @default.
• W2006377941 doi "https://doi.org/10.1530/eje-07-0252" @default.
• W2006377941 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17893268" @default.
• W2006377941 hasPublicationYear "2007" @default.
• W2006377941 type Work @default.
• W2006377941 sameAs 2006377941 @default.
• W2006377941 citedByCount "17" @default.
• W2006377941 countsByYear W20063779412013 @default.
• W2006377941 countsByYear W20063779412015 @default.
• W2006377941 countsByYear W20063779412016 @default.
• W2006377941 countsByYear W20063779412018 @default.
• W2006377941 countsByYear W20063779412019 @default.
• W2006377941 countsByYear W20063779412021 @default.
• W2006377941 countsByYear W20063779412022 @default.
• W2006377941 countsByYear W20063779412023 @default.
• W2006377941 crossrefType "journal-article" @default.
• W2006377941 hasAuthorship W2006377941A5002814926 @default.
• W2006377941 hasAuthorship W2006377941A5031402469 @default.
• W2006377941 hasAuthorship W2006377941A5076354360 @default.
• W2006377941 hasAuthorship W2006377941A5080872207 @default.
• W2006377941 hasAuthorship W2006377941A5089542434 @default.
• W2006377941 hasConcept C121608353 @default.
• W2006377941 hasConcept C126322002 @default.
• W2006377941 hasConcept C134018914 @default.
• W2006377941 hasConcept C167734588 @default.
• W2006377941 hasConcept C2776254400 @default.
• W2006377941 hasConcept C2777025900 @default.
• W2006377941 hasConcept C2777074255 @default.
• W2006377941 hasConcept C2779341817 @default.
• W2006377941 hasConcept C2779761222 @default.
• W2006377941 hasConcept C2781461381 @default.
• W2006377941 hasConcept C2909991657 @default.
• W2006377941 hasConcept C526584372 @default.
• W2006377941 hasConcept C71924100 @default.
• W2006377941 hasConcept C90924648 @default.
• W2006377941 hasConceptScore W2006377941C121608353 @default.
• W2006377941 hasConceptScore W2006377941C126322002 @default.
• W2006377941 hasConceptScore W2006377941C134018914 @default.
• W2006377941 hasConceptScore W2006377941C167734588 @default.
• W2006377941 hasConceptScore W2006377941C2776254400 @default.
• W2006377941 hasConceptScore W2006377941C2777025900 @default.
• W2006377941 hasConceptScore W2006377941C2777074255 @default.
• W2006377941 hasConceptScore W2006377941C2779341817 @default.
• W2006377941 hasConceptScore W2006377941C2779761222 @default.
• W2006377941 hasConceptScore W2006377941C2781461381 @default.
• W2006377941 hasConceptScore W2006377941C2909991657 @default.
• W2006377941 hasConceptScore W2006377941C526584372 @default.
• W2006377941 hasConceptScore W2006377941C71924100 @default.
• W2006377941 hasConceptScore W2006377941C90924648 @default.
• W2006377941 hasIssue "4" @default.
• W2006377941 hasLocation W20063779411 @default.
• W2006377941 hasLocation W20063779412 @default.
• W2006377941 hasOpenAccess W2006377941 @default.
• W2006377941 hasPrimaryLocation W20063779411 @default.
• W2006377941 hasRelatedWork W1980946234 @default.
• W2006377941 hasRelatedWork W2041173357 @default.

• next