FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2006385596> ?p ?o ?g. }

• W2006385596 endingPage "207" @default.
• W2006385596 startingPage "195" @default.
• W2006385596 abstract "Xanthine oxidoreductase (XOR), which is widely distributed from humans to bacteria, has a key role in purine catabolism, catalyzing two steps of sequential hydroxylation from hypoxanthine to xanthine and from xanthine to urate at its molybdenum cofactor (Moco). Human XOR is considered to be a target of drugs not only for therapy of hyperuricemia and gout, but also potentially for a wide variety of other diseases. In this review, we focus on studies of XOR inhibitors and their implications for understanding the chemical nature and reaction mechanism of the Moco active site of XOR. We also discuss further experimental or clinical studies that would be helpful to clarify remaining issues." @default.
• W2006385596 created "2016-06-24" @default.
• W2006385596 creator A5011237103 @default.
• W2006385596 creator A5056974084 @default.
• W2006385596 date "2014-12-12" @default.
• W2006385596 modified "2023-10-06" @default.
• W2006385596 title "Mechanistic insights into xanthine oxidoreductase from development studies of candidate drugs to treat hyperuricemia and gout" @default.
• W2006385596 cites W1485939620 @default.
• W2006385596 cites W1488225405 @default.
• W2006385596 cites W1489147212 @default.
• W2006385596 cites W1500295667 @default.
• W2006385596 cites W1519300281 @default.
• W2006385596 cites W1519698734 @default.
• W2006385596 cites W1527190561 @default.
• W2006385596 cites W1527247004 @default.
• W2006385596 cites W1568002412 @default.
• W2006385596 cites W1584018467 @default.
• W2006385596 cites W1584302732 @default.
• W2006385596 cites W15979421 @default.
• W2006385596 cites W1599183696 @default.
• W2006385596 cites W1605308536 @default.
• W2006385596 cites W16506711 @default.
• W2006385596 cites W1675570769 @default.
• W2006385596 cites W1680799029 @default.
• W2006385596 cites W1747820606 @default.
• W2006385596 cites W1785504137 @default.
• W2006385596 cites W1828830410 @default.
• W2006385596 cites W1866713406 @default.
• W2006385596 cites W1953423403 @default.
• W2006385596 cites W1965095095 @default.
• W2006385596 cites W1966002782 @default.
• W2006385596 cites W1967573492 @default.
• W2006385596 cites W1969294574 @default.
• W2006385596 cites W1969489400 @default.
• W2006385596 cites W1970627065 @default.
• W2006385596 cites W1971908845 @default.
• W2006385596 cites W1971923552 @default.
• W2006385596 cites W1973566510 @default.
• W2006385596 cites W1974398989 @default.
• W2006385596 cites W1976359888 @default.
• W2006385596 cites W1976697895 @default.
• W2006385596 cites W1978853108 @default.
• W2006385596 cites W1979308174 @default.
• W2006385596 cites W1981584366 @default.
• W2006385596 cites W1984586360 @default.
• W2006385596 cites W1984960406 @default.
• W2006385596 cites W1990266548 @default.
• W2006385596 cites W1993069257 @default.
• W2006385596 cites W1997469875 @default.
• W2006385596 cites W1998967175 @default.
• W2006385596 cites W1999711909 @default.
• W2006385596 cites W2002351719 @default.
• W2006385596 cites W2003059645 @default.
• W2006385596 cites W2004819407 @default.
• W2006385596 cites W2010109010 @default.
• W2006385596 cites W2010803354 @default.
• W2006385596 cites W2011899119 @default.
• W2006385596 cites W2014340299 @default.
• W2006385596 cites W2014886061 @default.
• W2006385596 cites W2020040322 @default.
• W2006385596 cites W2020253152 @default.
• W2006385596 cites W2021389477 @default.
• W2006385596 cites W2024984581 @default.
• W2006385596 cites W2025372788 @default.
• W2006385596 cites W2027365101 @default.
• W2006385596 cites W2028049009 @default.
• W2006385596 cites W2028547310 @default.
• W2006385596 cites W2029500385 @default.
• W2006385596 cites W2031000006 @default.
• W2006385596 cites W2031118520 @default.
• W2006385596 cites W2038247534 @default.
• W2006385596 cites W2039126859 @default.
• W2006385596 cites W2041775215 @default.
• W2006385596 cites W2043455550 @default.
• W2006385596 cites W2043884208 @default.
• W2006385596 cites W2044189561 @default.
• W2006385596 cites W2044444556 @default.
• W2006385596 cites W2045245826 @default.
• W2006385596 cites W2045251564 @default.
• W2006385596 cites W2045596790 @default.
• W2006385596 cites W2046419834 @default.
• W2006385596 cites W2046427323 @default.
• W2006385596 cites W2047204801 @default.
• W2006385596 cites W2047276432 @default.
• W2006385596 cites W2047956123 @default.
• W2006385596 cites W2052327619 @default.
• W2006385596 cites W2052448379 @default.
• W2006385596 cites W2052925570 @default.
• W2006385596 cites W2055422190 @default.
• W2006385596 cites W2057568012 @default.
• W2006385596 cites W2057637394 @default.
• W2006385596 cites W2058881562 @default.
• W2006385596 cites W2061672019 @default.
• W2006385596 cites W2062530945 @default.
• W2006385596 cites W2062754881 @default.
• W2006385596 cites W2063651018 @default.
• W2006385596 cites W2064157270 @default.
• W2006385596 cites W2064846828 @default.

• next