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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2006390045> ?p ?o ?g. }

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• W2006390045 abstract "In this study we report the synthesis and biological application of a novel cyclic nitrone spin trap containing a phosphonium cation. This new spin trap ([4-(2-methyl-1-oxy-3, 4-dihydro-2H-pyrrole-2-carbonyloxy)-butyl]-triphenyl-phosphonium bromide, MitoBMPOBr) is a derivative of the cyclic nitrone, 5-tert-butoxycarbonyl 5-methyl-1-pyrroline N-oxide (BMPO). MitoBMPOBr forms radical adducts upon trapping of superoxide and hydroxyl radicals that exhibit highly distinct and characteristic EPR spectra. The stability of these adducts is comparable to those of BMPO. Because of the presence of a positively-charged phosphonium moiety, MitoBMPOBr may be suitable for trapping reactive oxygen species (ROS) in the mitochondria." @default.
• W2006390045 created "2016-06-24" @default.
• W2006390045 creator A5035372773 @default.
• W2006390045 creator A5042575695 @default.
• W2006390045 date "2007-01-01" @default.
• W2006390045 modified "2023-10-14" @default.
• W2006390045 title "Synthesis and ESR studies of a novel cyclic nitrone spin trap attached to a phosphonium group-a suitable trap for mitochondria-generated ROS?" @default.
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• W2006390045 doi "https://doi.org/10.1080/10715760600911147" @default.
• W2006390045 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17164173" @default.
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