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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2006392854> ?p ?o ?g. }

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• W2006392854 abstract "This letter demonstrates a microfluidic platform for enumerating CD4+ T-lymphocytes from whole blood using chemiluminescence as a detection method. We microfabricated traps in a chamber and coated them with anti-CD4 antibody to isolate CD4+ T-cells. Based on cell surface-bound CD3 antibodies conjugated with horseradish peroxidase, incubation with chemiluminescent substrate produced a current in the photodetector that was proportional to the number of captured CD4+ T-cells. Analyzing 3 μL of whole blood, the platform exhibited high cell-capture efficiency and produced cell counts with high correlation to results obtained from flow cytometry. Compared to other lab-on-a-chip methods for CD4 counting, this method uses an instrument that requires no external light source and no image processing to produce a digitally displayed result only seconds after running the test." @default.
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• W2006392854 date "2009-11-25" @default.
• W2006392854 modified "2023-09-25" @default.
• W2006392854 title "Microfluidic CD4+ T-Cell Counting Device Using Chemiluminescence-Based Detection" @default.
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• W2006392854 doi "https://doi.org/10.1021/ac902144w" @default.
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