FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2006408894> ?p ?o ?g. }

• W2006408894 endingPage "578" @default.
• W2006408894 startingPage "564" @default.
• W2006408894 abstract "We evaluated the candidate tuberculosis vaccine M72/AS01 in Bacille-Calmette-Guérin (BCG)-vaccinated infants after or concomitantly with Expanded-Programme-on-Immunization (EPI) vaccines.In a Phase-II study in The Gambia (NCT01098474), 2 cohorts of 150 BCG-vaccinated infants each were randomized 1:1:1. The 'Outside-EPI' cohort received one or two M72/AS01 doses, or meningitis vaccine, 1-2 months after primary EPI vaccination. The 'Within-EPI' cohort received one or two M72/AS01 doses concomitantly with the third or last two doses of their primary EPI-regimen, respectively, or EPI vaccines alone. Safety, M72-specific humoral (ELISA) and cell-mediated (whole-blood ICS) responses, and humoral responses to EPI vaccines were assessed.M72/AS01 was acceptably tolerated with no vaccine-related serious adverse events reported. Seropositivity/seroprotection rates against EPI antigens in the Within-EPI cohort were comparable between groups, irrespective of M72/AS01 co-administration. Up to one year post M72/AS01 vaccination, M72-specific humoral and CD4(+) T-cell responses were higher after 2 doses versus 1 dose in both cohorts (p < 0.0001), and comparable between cohorts after either 1 or 2 doses (p > 0.05).M72/AS01 given to infants after or concomitantly with EPI vaccines had an acceptable safety profile. Our results suggest no interference of immunogenicity profiles occurred following co-administration of M72/AS01 and EPI vaccines. Two M72/AS01 doses elicited higher immune responses than one dose." @default.
• W2006408894 created "2016-06-24" @default.
• W2006408894 creator A5000582936 @default.
• W2006408894 creator A5011882174 @default.
• W2006408894 creator A5015037825 @default.
• W2006408894 creator A5015183702 @default.
• W2006408894 creator A5019029049 @default.
• W2006408894 creator A5026132977 @default.
• W2006408894 creator A5033423842 @default.
• W2006408894 creator A5038094743 @default.
• W2006408894 creator A5050043737 @default.
• W2006408894 creator A5051293616 @default.
• W2006408894 creator A5083056084 @default.
• W2006408894 date "2014-12-01" @default.
• W2006408894 modified "2023-09-28" @default.
• W2006408894 title "Safety and immunogenicity of the M72/AS01 candidate tuberculosis vaccine when given as a booster to BCG in Gambian infants: An open-label randomized controlled trial" @default.
• W2006408894 cites W1546213590 @default.
• W2006408894 cites W1582232949 @default.
• W2006408894 cites W1874438006 @default.
• W2006408894 cites W1941148137 @default.
• W2006408894 cites W1951330162 @default.
• W2006408894 cites W2000659418 @default.
• W2006408894 cites W2002319260 @default.
• W2006408894 cites W2007885803 @default.
• W2006408894 cites W2030226186 @default.
• W2006408894 cites W2066068520 @default.
• W2006408894 cites W2066738380 @default.
• W2006408894 cites W2067265452 @default.
• W2006408894 cites W2069039175 @default.
• W2006408894 cites W2074282824 @default.
• W2006408894 cites W2089226849 @default.
• W2006408894 cites W2097340122 @default.
• W2006408894 cites W2102179509 @default.
• W2006408894 cites W2103734560 @default.
• W2006408894 cites W2107876252 @default.
• W2006408894 cites W2108696062 @default.
• W2006408894 cites W2124515177 @default.
• W2006408894 cites W2125689304 @default.
• W2006408894 cites W2132657101 @default.
• W2006408894 cites W2140715538 @default.
• W2006408894 cites W2148681584 @default.
• W2006408894 cites W2149883005 @default.
• W2006408894 cites W2150785943 @default.
• W2006408894 cites W2155513799 @default.
• W2006408894 cites W2157559696 @default.
• W2006408894 cites W2160675125 @default.
• W2006408894 cites W2164944419 @default.
• W2006408894 cites W2295367859 @default.
• W2006408894 cites W2496549934 @default.
• W2006408894 cites W4205161959 @default.
• W2006408894 doi "https://doi.org/10.1016/j.tube.2014.07.001" @default.
• W2006408894 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25305000" @default.
• W2006408894 hasPublicationYear "2014" @default.
• W2006408894 type Work @default.
• W2006408894 sameAs 2006408894 @default.
• W2006408894 citedByCount "50" @default.
• W2006408894 countsByYear W20064088942015 @default.
• W2006408894 countsByYear W20064088942016 @default.
• W2006408894 countsByYear W20064088942017 @default.
• W2006408894 countsByYear W20064088942018 @default.
• W2006408894 countsByYear W20064088942019 @default.
• W2006408894 countsByYear W20064088942020 @default.
• W2006408894 countsByYear W20064088942021 @default.
• W2006408894 countsByYear W20064088942022 @default.
• W2006408894 countsByYear W20064088942023 @default.
• W2006408894 crossrefType "journal-article" @default.
• W2006408894 hasAuthorship W2006408894A5000582936 @default.
• W2006408894 hasAuthorship W2006408894A5011882174 @default.
• W2006408894 hasAuthorship W2006408894A5015037825 @default.
• W2006408894 hasAuthorship W2006408894A5015183702 @default.
• W2006408894 hasAuthorship W2006408894A5019029049 @default.
• W2006408894 hasAuthorship W2006408894A5026132977 @default.
• W2006408894 hasAuthorship W2006408894A5033423842 @default.
• W2006408894 hasAuthorship W2006408894A5038094743 @default.
• W2006408894 hasAuthorship W2006408894A5050043737 @default.
• W2006408894 hasAuthorship W2006408894A5051293616 @default.
• W2006408894 hasAuthorship W2006408894A5083056084 @default.
• W2006408894 hasBestOaLocation W20064088941 @default.
• W2006408894 hasConcept C12590561 @default.
• W2006408894 hasConcept C203014093 @default.
• W2006408894 hasConcept C22070199 @default.
• W2006408894 hasConcept C2780801004 @default.
• W2006408894 hasConcept C2780868878 @default.
• W2006408894 hasConcept C71924100 @default.
• W2006408894 hasConcept C8891405 @default.
• W2006408894 hasConceptScore W2006408894C12590561 @default.
• W2006408894 hasConceptScore W2006408894C203014093 @default.
• W2006408894 hasConceptScore W2006408894C22070199 @default.
• W2006408894 hasConceptScore W2006408894C2780801004 @default.
• W2006408894 hasConceptScore W2006408894C2780868878 @default.
• W2006408894 hasConceptScore W2006408894C71924100 @default.
• W2006408894 hasConceptScore W2006408894C8891405 @default.
• W2006408894 hasFunder F4320311178 @default.
• W2006408894 hasIssue "6" @default.
• W2006408894 hasLocation W20064088941 @default.
• W2006408894 hasLocation W20064088942 @default.
• W2006408894 hasOpenAccess W2006408894 @default.
• W2006408894 hasPrimaryLocation W20064088941 @default.

• next