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• W2006463485 abstract "Progesterone plays an important role in sperm capacitation and acrosome reaction. In this experiment we examined the effect of a progesterone antagonist, RU486, on the penetration of zona-free hamster eggs by human sperm. Media containing 10, 15, 20, 25 or 30 μM RU486 were prepared. In the control medium without RU486, the sperm penetration rate was 80.7%. In the medium with 10 μM RU486, the sperm penetration rate was 67.0%. The rate further decreased as the level of RU486 increased. In the medium with 30 μM RU486, the sperm penetration rate was reduced to 4.8%. This study demonstrates that RU486 inhibits penetration of zona-free hamster eggs by human sperm in a dose-dependent manner." @default.
• W2006463485 created "2016-06-24" @default.
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• W2006463485 creator A5063901605 @default.
• W2006463485 date "1997-01-01" @default.
• W2006463485 modified "2023-09-25" @default.
• W2006463485 title "Effects of Competitive Progesterone Antagonist RU486 on the Penetration of Zona-Free Hamster Eggs by Human Sperm." @default.
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• W2006463485 doi "https://doi.org/10.1274/jmor.14.180" @default.
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