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• W2006494462 abstract "<h2>ABSTRACT</h2><h3>Objective</h3> To assess the ability of ultrasound studies, performed by an experienced clinician, to predict surgical findings and provide precise anatomic localization of abnormal parathyroid glands. <h3>Methods</h3> We retrospectively examined 200 consecutive parathyroid ultrasound studies performed by a single experienced clinician in our unit. All patients subsequently underwent parathyroidectomy, with histopathologic confirmation of abnormal parathyroid tissue. The correlation between the ultrasound and surgical findings was assessed. <h3>Results</h3> Of the 200 study patients, 197 (98.5%) were cured of their disease at the initial operation. Ultrasound studies correctly predicted the surgical findings in 88% of patients, including 168 of 180 (93%) with single gland disease and 7 of 20 (35%) with multiple gland disease (MGD). In all cases in which a single adenoma was identified, precise information regarding its location relative to adjacent anatomic structures was provided. In 92% of these cases, anatomic details correlated closely with surgical findings. Ectopic and descended superior adenomas were most frequently missed. Patients with two nonlocalizing studies (scintigraphy and ultrasonography) had a >50% likelihood of having MGD. <h3>Conclusion</h3> In experienced hands, parathyroid ultrasonography is a highly sensitive technique that provides both localization of enlarged parathyroid glands and precise anatomic detail. Thus, in this study, focused parathyroidectomy was possible in 76.5% of patients. MGD remains difficult to diagnose preoperatively. Non-localizing studies should alert the surgeon to a high probability of MGD and prompt the performance of 4-gland exploration. <b>(Endocr Pract. 2006;12:257-263)</b>" @default.
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• W2006494462 date "2006-05-01" @default.
• W2006494462 modified "2023-09-29" @default.
• W2006494462 title "Two Hundred Consecutive Parathyroid Ultrasound Studies by a Single Clinician: The Impact of Experience" @default.
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• W2006494462 doi "https://doi.org/10.4158/ep.12.3.257" @default.
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