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- W2006497838 abstract "AbstractThe thalamus has been implicated in having an important role in pain processing in chronic neuropathic pain patients in recent imaging studies. The purpose of this study was to examine the correlation of the N-acetylaspartate to creatine (NAA/Cr) ratio measured by proton magnetic resonance spectroscopy (1H-MRS), which reflects neural function, with regional cerebral blood flow (rCBF) in the thalamus of chronic neuropathic pain patients. We performed 1H-MRS with a 1.5T MR system on a 2×2×2 cm voxel in the thalamus bilaterally in six patients with chronic neuropathic pain (CRPS type-1, 4; central post-stroke pain; 2). We compared NAA/Cr ratios measured by 1H-MRS to rCBF measured by 99mTc ECD SPECT. The asymmetry index of the NAA/Cr ratio, which was defined as contralateral/ipsilateral ratio, was significantly positively correlated with the asymmetry index of rCBF (r = 0.94; p < 0.05). Our results using 1H-MRS show that neural function of the thalamus may be associated with rCBF." @default.
- W2006497838 created "2016-06-24" @default.
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- W2006497838 date "2002-08-01" @default.
- W2006497838 modified "2023-09-28" @default.
- W2006497838 title "Evaluation of thalamic neural function in chronic neuropathic pain patients by proton MR spectroscopy: a correlative study with rCBF by SPECT" @default.
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- W2006497838 doi "https://doi.org/10.1163/156856902760196397" @default.
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