Matches in SemOpenAlex for { <https://semopenalex.org/work/W2006531671> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2006531671 endingPage "86" @default.
- W2006531671 startingPage "79" @default.
- W2006531671 abstract "Veillonella alcalescens during lactate degradation developed an Na+ concentration gradient with 7-8 times higher external than internal Na+ concentrations in the logarithmic growth phase. The gradient declined to a factor of 1.9 in the late stationary phase. Methylmalonyl-CoA decarboxylase reconstituted into proteoliposomes performed an active electrogenic Na+ transport, creating delta psi of 60 mV, delta pNa+ of 50 mV, and delta mu Na+ of 110 mV. In the initial phase of the transport, the decarboxylase catalyzed the uptake of 2 Na+ ions malonyl-CoA molecule decarboxylated. During further development of the electrochemical Na+ gradient, this ratio gradually declined to zero, when decarboxylation continued without further increase of the internal Na+ concentration. The rate of malonyl-CoA decarboxylation declined initially during development of the membrane potential, but remained unchanged later on. Monensin abolished the Na+ gradient and increased the malonyl-CoA decarboxylation rate 2.8-fold. On dissipating the membrane potential with valinomycin, the internal Na+ concentration reached three times higher values than in its absence, and the decarboxylation rate increased 2.8-fold. Methylmalonyl-CoA decarboxylase catalyzed an exchange of internal and external Na+ ions in addition to net Na+ accumulation. The initial rate of Na+ influx was double that of malonyl-CoA decarboxylation. In the following, both rates decreased about twofold in parallel to values which remained constant during further development of the electrochemical Na+ gradient. Thus, Na+ influx and malonyl-CoA decarboxylation follow a stoichiometry of approximately 2:1, independent of the magnitude of the electrochemical Na+ gradient and are thus highly coupled events." @default.
- W2006531671 created "2016-06-24" @default.
- W2006531671 creator A5000429181 @default.
- W2006531671 creator A5076622073 @default.
- W2006531671 date "1991-01-01" @default.
- W2006531671 modified "2023-09-30" @default.
- W2006531671 title "On the mechanism of sodium ion translocation by methylmalonyl-CoA decarboxylase from Veillonella alcalescens" @default.
- W2006531671 cites W1487284562 @default.
- W2006531671 cites W1529748011 @default.
- W2006531671 cites W1562871643 @default.
- W2006531671 cites W1565432362 @default.
- W2006531671 cites W1573238696 @default.
- W2006531671 cites W1594934722 @default.
- W2006531671 cites W1775749144 @default.
- W2006531671 cites W1927165718 @default.
- W2006531671 cites W1972114225 @default.
- W2006531671 cites W1986546093 @default.
- W2006531671 cites W1990021323 @default.
- W2006531671 cites W2014573850 @default.
- W2006531671 cites W2021618924 @default.
- W2006531671 cites W2041143211 @default.
- W2006531671 cites W2052110396 @default.
- W2006531671 cites W2054468307 @default.
- W2006531671 cites W2062097010 @default.
- W2006531671 cites W2072913548 @default.
- W2006531671 cites W2077056234 @default.
- W2006531671 cites W2079132360 @default.
- W2006531671 cites W2091351440 @default.
- W2006531671 cites W2125727238 @default.
- W2006531671 cites W2162660905 @default.
- W2006531671 cites W258559763 @default.
- W2006531671 cites W4246026011 @default.
- W2006531671 doi "https://doi.org/10.1111/j.1432-1033.1991.tb15678.x" @default.
- W2006531671 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1991479" @default.
- W2006531671 hasPublicationYear "1991" @default.
- W2006531671 type Work @default.
- W2006531671 sameAs 2006531671 @default.
- W2006531671 citedByCount "30" @default.
- W2006531671 countsByYear W20065316712013 @default.
- W2006531671 countsByYear W20065316712015 @default.
- W2006531671 countsByYear W20065316712017 @default.
- W2006531671 countsByYear W20065316712020 @default.
- W2006531671 countsByYear W20065316712021 @default.
- W2006531671 countsByYear W20065316712022 @default.
- W2006531671 crossrefType "journal-article" @default.
- W2006531671 hasAuthorship W2006531671A5000429181 @default.
- W2006531671 hasAuthorship W2006531671A5076622073 @default.
- W2006531671 hasBestOaLocation W20065316711 @default.
- W2006531671 hasConcept C147789679 @default.
- W2006531671 hasConcept C155647269 @default.
- W2006531671 hasConcept C161790260 @default.
- W2006531671 hasConcept C17525397 @default.
- W2006531671 hasConcept C178790620 @default.
- W2006531671 hasConcept C179104552 @default.
- W2006531671 hasConcept C185592680 @default.
- W2006531671 hasConcept C2780595602 @default.
- W2006531671 hasConcept C41625074 @default.
- W2006531671 hasConcept C52859227 @default.
- W2006531671 hasConcept C537181965 @default.
- W2006531671 hasConcept C55493867 @default.
- W2006531671 hasConcept C71240020 @default.
- W2006531671 hasConcept C90424259 @default.
- W2006531671 hasConceptScore W2006531671C147789679 @default.
- W2006531671 hasConceptScore W2006531671C155647269 @default.
- W2006531671 hasConceptScore W2006531671C161790260 @default.
- W2006531671 hasConceptScore W2006531671C17525397 @default.
- W2006531671 hasConceptScore W2006531671C178790620 @default.
- W2006531671 hasConceptScore W2006531671C179104552 @default.
- W2006531671 hasConceptScore W2006531671C185592680 @default.
- W2006531671 hasConceptScore W2006531671C2780595602 @default.
- W2006531671 hasConceptScore W2006531671C41625074 @default.
- W2006531671 hasConceptScore W2006531671C52859227 @default.
- W2006531671 hasConceptScore W2006531671C537181965 @default.
- W2006531671 hasConceptScore W2006531671C55493867 @default.
- W2006531671 hasConceptScore W2006531671C71240020 @default.
- W2006531671 hasConceptScore W2006531671C90424259 @default.
- W2006531671 hasIssue "1" @default.
- W2006531671 hasLocation W20065316711 @default.
- W2006531671 hasLocation W20065316712 @default.
- W2006531671 hasOpenAccess W2006531671 @default.
- W2006531671 hasPrimaryLocation W20065316711 @default.
- W2006531671 hasRelatedWork W2008290590 @default.
- W2006531671 hasRelatedWork W2060566628 @default.
- W2006531671 hasRelatedWork W2150967171 @default.
- W2006531671 hasRelatedWork W2355151844 @default.
- W2006531671 hasRelatedWork W2405385153 @default.
- W2006531671 hasRelatedWork W2406910599 @default.
- W2006531671 hasRelatedWork W2949503151 @default.
- W2006531671 hasRelatedWork W2950538501 @default.
- W2006531671 hasRelatedWork W2951533543 @default.
- W2006531671 hasRelatedWork W2952184001 @default.
- W2006531671 hasVolume "195" @default.
- W2006531671 isParatext "false" @default.
- W2006531671 isRetracted "false" @default.
- W2006531671 magId "2006531671" @default.
- W2006531671 workType "article" @default.