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• W2006562402 abstract "Summary Chronic infection with the hepatitis B virus ( HBV ) is a frequent cause of cirrhosis and liver cancer. Targeted HBV screening is recommended by the Centre for Disease Control (CDC) and Prevention for subjects born in countries with >2% HBV prevalence. However, there are no UK guidelines. Here, we applied the ( CDC ) recommendations to the British–Chinese and British–South Asian community of North‐East (NE) England. British–Chinese and South Asian subjects were invited to attend for HBV education and screening sessions held in community centres. Hepatitis B surface antigen ( HB sAg) and hepatitis B core total antibody ( HB cAb) were tested with dry blood spot tests. South Asians were also tested for hepatitis C antibody ( HCVA b). A total of 1126 subjects (606 Chinese and 520 South Asian) were screened. Sixty‐two (5.5%) were HB sAg positive. Ten of these reported a previous diagnosis of HBV . The prevalence of HB sAg positivity was 4.6% when previously diagnosed individuals were excluded. The HB sAg prevalence was significantly higher in the Chinese subjects compared with South Asians (8.7% VS . 1.7% P < 0.001). In Chinese subjects, HB sAg positivity was highest in subjects born in Vietnam (17.4%), followed by China (11%), Hong Kong (7.8%) and the UK (6.7%). Subjects from Pakistan had the highest HB sAg and HCV Ab prevalence in the South Asians (3.1% and 1.8%, respectively). Ten percentage of HB sAg positive patients who had follow‐up assessment had active disease requiring antiviral treatment. Undiagnosed HBV infection was above the 2% threshold for screening suggested by the CDC in the British–Chinese and Pakistani community of NE England, which provides evidence for a UK HBV ‐targeted screening programme." @default.
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• W2006562402 date "2013-03-12" @default.
• W2006562402 modified "2023-10-13" @default.
• W2006562402 title "Targeted case finding for hepatitis B using dry blood spot testing in the British-Chinese and South Asian populations of the North-East of England" @default.
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• W2006562402 doi "https://doi.org/10.1111/jvh.12084" @default.
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