Matches in SemOpenAlex for { <https://semopenalex.org/work/W2006571105> ?p ?o ?g. }
- W2006571105 endingPage "270" @default.
- W2006571105 startingPage "270" @default.
- W2006571105 abstract "The prevalence of neoplastic pericardial diseases has changed over time and varies according to diagnostic methods. The diagnostic factor is usually the detection of neoplastic cells within the pericardial fluid or in specimens of pericardium, but the diagnosis may be difficult. Accurate sampling and cytopreparatory techniques, together with ancillary studies, including immunohistochemical tests and neoplastic marker dosage, are essential to obtain a reliable diagnosis. The goals of treatment may be simply to relieve symptoms (cardiac tamponade or dyspnea), to prevent recurrent effusion for a long-term symptomatic benefit, or to treat the local neoplastic disease with the aim of prolonging survival. Immediate relief of symptoms may be obtained with percutaneous drainage or with a surgical approach. For long term prevention of recurrences, various approaches have been proposed: extended drainage, pericardial window (surgical or percutaneous balloon pericardiostomy), sclerosing local therapy, local and/or systemic chemotherapy or radiation therapy (RT) (external or with intrapericardial radionuclides). The outcomes of various therapeutic approaches vary for different tumor types. Lymphoma and leukemias can be successfully treated with systemic chemotherapy; for solid tumors, percutaneous drainage and the use of systemic and/or local sclerosing and antineoplastic therapy seems to offer the best chance of success. The use of pure sclerosing agents has been replaced by agents with both sclerosing and antineoplastic activity (bleomycin or thiotepa), which seems to be quite effective in breast cancer, at least when associated with systemic chemotherapy. Local chemotherapy with platinum, mitoxantrone and other agents may lead to good local control of the disease, but the addition of systemic chemotherapy is probably relevant in order to prolong survival. The surgical approach (creation of a pericardial window, even with the mini-invasive method of balloon pericardiostomy) and RT may be useful in recurring effusions or in cases that are refractory to other therapeutic approaches." @default.
- W2006571105 created "2016-06-24" @default.
- W2006571105 creator A5016082541 @default.
- W2006571105 date "2010-01-01" @default.
- W2006571105 modified "2023-10-14" @default.
- W2006571105 title "Neoplastic pericardial disease: Old and current strategies for diagnosis and management" @default.
- W2006571105 cites W1822653403 @default.
- W2006571105 cites W1843274629 @default.
- W2006571105 cites W1948603126 @default.
- W2006571105 cites W1963909042 @default.
- W2006571105 cites W1966112821 @default.
- W2006571105 cites W1966238615 @default.
- W2006571105 cites W1966418235 @default.
- W2006571105 cites W1967624456 @default.
- W2006571105 cites W1968434446 @default.
- W2006571105 cites W1975874476 @default.
- W2006571105 cites W1976473782 @default.
- W2006571105 cites W1977767138 @default.
- W2006571105 cites W1979157170 @default.
- W2006571105 cites W1981393875 @default.
- W2006571105 cites W1983698607 @default.
- W2006571105 cites W1984152298 @default.
- W2006571105 cites W1984628336 @default.
- W2006571105 cites W1989762868 @default.
- W2006571105 cites W1990948656 @default.
- W2006571105 cites W1991574927 @default.
- W2006571105 cites W1993652259 @default.
- W2006571105 cites W1995556138 @default.
- W2006571105 cites W1995807385 @default.
- W2006571105 cites W1997345401 @default.
- W2006571105 cites W1998146264 @default.
- W2006571105 cites W1998497285 @default.
- W2006571105 cites W1999874075 @default.
- W2006571105 cites W2000396934 @default.
- W2006571105 cites W2002177822 @default.
- W2006571105 cites W2006907493 @default.
- W2006571105 cites W2007273118 @default.
- W2006571105 cites W2010248667 @default.
- W2006571105 cites W2011908933 @default.
- W2006571105 cites W2013197994 @default.
- W2006571105 cites W2018228994 @default.
- W2006571105 cites W2019786363 @default.
- W2006571105 cites W2022454119 @default.
- W2006571105 cites W2023028488 @default.
- W2006571105 cites W2023053625 @default.
- W2006571105 cites W2024295534 @default.
- W2006571105 cites W2024822012 @default.
- W2006571105 cites W2025316216 @default.
- W2006571105 cites W2026567790 @default.
- W2006571105 cites W2031486021 @default.
- W2006571105 cites W2032559780 @default.
- W2006571105 cites W2034867758 @default.
- W2006571105 cites W2042384267 @default.
- W2006571105 cites W2044260483 @default.
- W2006571105 cites W2045148473 @default.
- W2006571105 cites W2046337633 @default.
- W2006571105 cites W2046657022 @default.
- W2006571105 cites W2051066728 @default.
- W2006571105 cites W2051175539 @default.
- W2006571105 cites W2053118445 @default.
- W2006571105 cites W2054240911 @default.
- W2006571105 cites W2057797579 @default.
- W2006571105 cites W2058697232 @default.
- W2006571105 cites W2059175983 @default.
- W2006571105 cites W2059258280 @default.
- W2006571105 cites W2062483284 @default.
- W2006571105 cites W2062739503 @default.
- W2006571105 cites W2063250880 @default.
- W2006571105 cites W2065984000 @default.
- W2006571105 cites W2066275332 @default.
- W2006571105 cites W2066939567 @default.
- W2006571105 cites W2068279460 @default.
- W2006571105 cites W2068348977 @default.
- W2006571105 cites W2077525882 @default.
- W2006571105 cites W2079871339 @default.
- W2006571105 cites W2083344543 @default.
- W2006571105 cites W2084630485 @default.
- W2006571105 cites W2086094268 @default.
- W2006571105 cites W2087122055 @default.
- W2006571105 cites W2091716234 @default.
- W2006571105 cites W2092156160 @default.
- W2006571105 cites W2093055238 @default.
- W2006571105 cites W2094298377 @default.
- W2006571105 cites W2103747159 @default.
- W2006571105 cites W2104967608 @default.
- W2006571105 cites W2106238430 @default.
- W2006571105 cites W2111812363 @default.
- W2006571105 cites W2112900456 @default.
- W2006571105 cites W2113330833 @default.
- W2006571105 cites W2123787954 @default.
- W2006571105 cites W2126409357 @default.
- W2006571105 cites W2133435220 @default.
- W2006571105 cites W2135143262 @default.
- W2006571105 cites W2141075174 @default.
- W2006571105 cites W2150879166 @default.
- W2006571105 cites W2157882162 @default.
- W2006571105 cites W2158353647 @default.
- W2006571105 cites W2158958376 @default.