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- W2006571822 abstract "Walther Wernsdorfer recently outlined the many factors that could have contributed to the serious problem of drug-resistant malaria ~ . He, and others 2, tacitly accept that host antimalarial immunity enhances chemotherapeutic efficacy but the corollaries of this hypothesis are seldom discussed, namely, that drug efficacy is therefore likely to be impaired in hosts that are immunosuppressed, and that treatment in such circumstances could very well favour selection of drug-resistant organisms. The arguments, with supporting evidence, have been rehearsed at greater length elsewhere 3'4, and would seem to be amenable to field testing. If validated, their importance is clear in times of such rapidly increasing numbers of immunosuppressed people in many malaria-endemic areas." @default.
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- W2006571822 date "1992-04-01" @default.
- W2006571822 modified "2023-09-27" @default.
- W2006571822 title "Does immunosuppression promote drug resistance in malaria?" @default.
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- W2006571822 doi "https://doi.org/10.1016/0169-4758(92)90282-7" @default.
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