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• W2006578086 abstract "The design and synthesis of a new series of high efficacy β2-agonists devoid of the key benzylic alcohol present in previously described highly efficacious β2-agonists is reported. A hypothesis for the unprecedented level of efficacy is proposed based on considerations of β2-adrenoceptor crystal structure, other biophysical data and modeling studies." @default.
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• W2006578086 date "2011-07-01" @default.
• W2006578086 modified "2023-09-27" @default.
• W2006578086 title "Design driven HtL: The discovery and synthesis of new high efficacy β 2 -agonists" @default.
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• W2006578086 doi "https://doi.org/10.1016/j.bmcl.2011.04.135" @default.
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