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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2006579501> ?p ?o ?g. }

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• W2006579501 abstract "The structure of a soluble homopentameric homologue of the N-terminal extracellular domain of the nicotinic acetylcholine (ACh) receptor has recently been determined at the atomic level. These data reveal the three-dimensional structure of the binding site for ACh and nicotinic ligands. The ACh-binding sites are located at subunit boundaries in an equatorial position and are framed by residues previously identified in nicotinic receptors, by photoaffinity labelling and mutagenesis experiments, as being crucial for ligand binding. On this basis, a hypothetical mechanism for the allosteric transitions of the nicotinic receptors is suggested." @default.
• W2006579501 created "2016-06-24" @default.
• W2006579501 creator A5008000898 @default.
• W2006579501 creator A5056074308 @default.
• W2006579501 date "2001-08-01" @default.
• W2006579501 modified "2023-10-16" @default.
• W2006579501 title "Nicotinic receptors in wonderland" @default.
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• W2006579501 doi "https://doi.org/10.1016/s0968-0004(01)01921-1" @default.
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