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• W2006593239 endingPage "324" @default.
• W2006593239 startingPage "309" @default.
• W2006593239 abstract "Our perception of intracellular organelles and cellular architecture was initially based on striking light and electron micrographs of animal and plant cells. The high degree of compartmental organization within specialized mammalian secretory cells aided early efforts to track the movement of proteins through the organelles of the secretory pathway. In contrast, the morphological detail of the yeast Saccharomyces cerevisiae appeared superficially simple, even primitive, by comparison with the higher eukaryotic cells. However, the combination of genetic tools and the development of assays reconstituting vesicular traffic in yeast have facilitated the identification and characterization of individual proteins that function in the secretory pathway. Analogies between the function of yeast and mammalian proteins in vesicular traffic are being drawn with increasing frequency. In this review, the combination of genetic, biochemical, molecular and cell biological approaches used to study compartmental organization in the yeast secretory pathway will be discussed. The rapid progress in our understanding of yeast membrane traffic has revealed the beauty of working with this organism." @default.
• W2006593239 created "2016-06-24" @default.
• W2006593239 creator A5068158283 @default.
• W2006593239 date "1992-10-01" @default.
• W2006593239 modified "2023-09-26" @default.
• W2006593239 title "Beauty and the yeast: compartmental organization of the secretory pathway" @default.
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