Matches in SemOpenAlex for { <https://semopenalex.org/work/W2006630116> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W2006630116 endingPage "452" @default.
- W2006630116 startingPage "447" @default.
- W2006630116 abstract "Beneficial effects of calcium antagonists on the pulmonary haemodynamics of patients with chronic obstructive pulmonary disease (COPD) have been observed in several studies. Such effects include a decrease in pulmonary vascular resistance, an increase in cardiac output, and an increase in oxygen delivery. The clinical implications of these effects are uncertain. The randomized, double-blind, placebo-controlled, long-term study described here is the first to investigate the clinical effects of a calcium antagonist on patients with COPD. The aim was to test the hypothesis that the calcium antagonist, isradipine, could increase working capacity and lung function, and decrease morbidity and mortality. Fifty-two patients with COPD were investigated. During a 22-month observation period no statistically significant differences between the isradipine group and the placebo group were found with regard to these parameters. It is concluded that the existing evidence does not justify the introduction of calcium antagonists as part of the routine treatment of COPD." @default.
- W2006630116 created "2016-06-24" @default.
- W2006630116 creator A5010364201 @default.
- W2006630116 creator A5021439217 @default.
- W2006630116 creator A5033919001 @default.
- W2006630116 creator A5045994384 @default.
- W2006630116 creator A5055750849 @default.
- W2006630116 date "1991-05-01" @default.
- W2006630116 modified "2023-10-16" @default.
- W2006630116 title "The effect of the calcium antagonist, isradipine, on working capacity, pulmonary function, morbidity and survival rate in patients with severe chronic obstructive pulmonary disease (COPD): a randomized, double-blind, placebo-controlled study" @default.
- W2006630116 cites W1859286706 @default.
- W2006630116 cites W1964138516 @default.
- W2006630116 cites W1965812641 @default.
- W2006630116 cites W2022022283 @default.
- W2006630116 cites W2045748286 @default.
- W2006630116 cites W2061098585 @default.
- W2006630116 cites W2094898334 @default.
- W2006630116 cites W2102358976 @default.
- W2006630116 cites W2103001098 @default.
- W2006630116 cites W2152141229 @default.
- W2006630116 cites W2152503242 @default.
- W2006630116 cites W2338429321 @default.
- W2006630116 cites W2344312360 @default.
- W2006630116 cites W4205209053 @default.
- W2006630116 doi "https://doi.org/10.1111/j.1365-2796.1991.tb00373.x" @default.
- W2006630116 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1828266" @default.
- W2006630116 hasPublicationYear "1991" @default.
- W2006630116 type Work @default.
- W2006630116 sameAs 2006630116 @default.
- W2006630116 citedByCount "2" @default.
- W2006630116 crossrefType "journal-article" @default.
- W2006630116 hasAuthorship W2006630116A5010364201 @default.
- W2006630116 hasAuthorship W2006630116A5021439217 @default.
- W2006630116 hasAuthorship W2006630116A5033919001 @default.
- W2006630116 hasAuthorship W2006630116A5045994384 @default.
- W2006630116 hasAuthorship W2006630116A5055750849 @default.
- W2006630116 hasConcept C126322002 @default.
- W2006630116 hasConcept C142724271 @default.
- W2006630116 hasConcept C164705383 @default.
- W2006630116 hasConcept C168563851 @default.
- W2006630116 hasConcept C170493617 @default.
- W2006630116 hasConcept C204787440 @default.
- W2006630116 hasConcept C27081682 @default.
- W2006630116 hasConcept C2776066529 @default.
- W2006630116 hasConcept C2776780178 @default.
- W2006630116 hasConcept C2776885963 @default.
- W2006630116 hasConcept C2780930700 @default.
- W2006630116 hasConcept C42219234 @default.
- W2006630116 hasConcept C71924100 @default.
- W2006630116 hasConcept C75603125 @default.
- W2006630116 hasConceptScore W2006630116C126322002 @default.
- W2006630116 hasConceptScore W2006630116C142724271 @default.
- W2006630116 hasConceptScore W2006630116C164705383 @default.
- W2006630116 hasConceptScore W2006630116C168563851 @default.
- W2006630116 hasConceptScore W2006630116C170493617 @default.
- W2006630116 hasConceptScore W2006630116C204787440 @default.
- W2006630116 hasConceptScore W2006630116C27081682 @default.
- W2006630116 hasConceptScore W2006630116C2776066529 @default.
- W2006630116 hasConceptScore W2006630116C2776780178 @default.
- W2006630116 hasConceptScore W2006630116C2776885963 @default.
- W2006630116 hasConceptScore W2006630116C2780930700 @default.
- W2006630116 hasConceptScore W2006630116C42219234 @default.
- W2006630116 hasConceptScore W2006630116C71924100 @default.
- W2006630116 hasConceptScore W2006630116C75603125 @default.
- W2006630116 hasIssue "5" @default.
- W2006630116 hasLocation W20066301161 @default.
- W2006630116 hasLocation W20066301162 @default.
- W2006630116 hasOpenAccess W2006630116 @default.
- W2006630116 hasPrimaryLocation W20066301161 @default.
- W2006630116 hasRelatedWork W2168449172 @default.
- W2006630116 hasRelatedWork W2357524925 @default.
- W2006630116 hasRelatedWork W2362299873 @default.
- W2006630116 hasRelatedWork W2372071230 @default.
- W2006630116 hasRelatedWork W2480324658 @default.
- W2006630116 hasRelatedWork W2884099160 @default.
- W2006630116 hasRelatedWork W3029067760 @default.
- W2006630116 hasRelatedWork W3030375482 @default.
- W2006630116 hasRelatedWork W3119562397 @default.
- W2006630116 hasRelatedWork W4235671539 @default.
- W2006630116 hasVolume "229" @default.
- W2006630116 isParatext "false" @default.
- W2006630116 isRetracted "false" @default.
- W2006630116 magId "2006630116" @default.
- W2006630116 workType "article" @default.