Matches in SemOpenAlex for { <https://semopenalex.org/work/W2006642837> ?p ?o ?g. }
- W2006642837 endingPage "205" @default.
- W2006642837 startingPage "199" @default.
- W2006642837 abstract "Intermedin/Adrenomedullin-2 (IMD), a newly described peptide with structural homology to adrenomedullin (AM), is present in brain and pituitary gland and binds to the same receptors as AM and calcitonin gene-related peptide (CGRP). We hypothesized that IMD would exert actions similar to AM and CGRP and previously have demonstrated that indeed IMD, like AM and CGRP, increases sympathetic tone and inhibits feeding and drinking when administered centrally. Here, we extend those observations by demonstrating that like AM, IMD acts in brain to stimulate the secretions of prolactin (PRL) and adrenocorticotropin (ACTH) and to inhibit the secretion of growth hormone (GH) in conscious rats. In addition, in conscious rats, central administration of IMD results in increased plasma levels of oxytocin (OT) and vasopressin (AVP). The ability of IMD to activate the hypothalamo-pituitary-adrenal (HPA) axis can be blocked by intravenous pretreatment with the corticotropin releasing factor (CRF) antagonist, astressin. These results suggest that multiple members of the AM family of peptides may be involved in the cardiovascular, behavioral and neuroendocrine responses to stress." @default.
- W2006642837 created "2016-06-24" @default.
- W2006642837 creator A5003608252 @default.
- W2006642837 creator A5059960680 @default.
- W2006642837 date "2005-05-01" @default.
- W2006642837 modified "2023-10-14" @default.
- W2006642837 title "Stress hormone secretion is altered by central administration of intermedin/adrenomedullin-2" @default.
- W2006642837 cites W1978011471 @default.
- W2006642837 cites W1978775244 @default.
- W2006642837 cites W1981578013 @default.
- W2006642837 cites W1982974243 @default.
- W2006642837 cites W1989419353 @default.
- W2006642837 cites W1993026029 @default.
- W2006642837 cites W1998092526 @default.
- W2006642837 cites W2009800112 @default.
- W2006642837 cites W2017606763 @default.
- W2006642837 cites W2020159446 @default.
- W2006642837 cites W2020574577 @default.
- W2006642837 cites W2024660080 @default.
- W2006642837 cites W2024972153 @default.
- W2006642837 cites W2031081542 @default.
- W2006642837 cites W2039578628 @default.
- W2006642837 cites W2043654095 @default.
- W2006642837 cites W2044285853 @default.
- W2006642837 cites W2048988471 @default.
- W2006642837 cites W2049641826 @default.
- W2006642837 cites W2049876031 @default.
- W2006642837 cites W2053277833 @default.
- W2006642837 cites W2064119007 @default.
- W2006642837 cites W2066469292 @default.
- W2006642837 cites W2076178177 @default.
- W2006642837 cites W2076206755 @default.
- W2006642837 cites W2076714823 @default.
- W2006642837 cites W2078304896 @default.
- W2006642837 cites W2078687232 @default.
- W2006642837 cites W2083160864 @default.
- W2006642837 cites W2086403888 @default.
- W2006642837 cites W2086574534 @default.
- W2006642837 cites W2088752114 @default.
- W2006642837 cites W2095354033 @default.
- W2006642837 cites W2102917831 @default.
- W2006642837 cites W2104549499 @default.
- W2006642837 cites W2105790528 @default.
- W2006642837 cites W2110699104 @default.
- W2006642837 cites W2148979367 @default.
- W2006642837 cites W2162014506 @default.
- W2006642837 cites W2305627972 @default.
- W2006642837 cites W2322158431 @default.
- W2006642837 cites W2416125425 @default.
- W2006642837 doi "https://doi.org/10.1016/j.brainres.2005.03.034" @default.
- W2006642837 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15910778" @default.
- W2006642837 hasPublicationYear "2005" @default.
- W2006642837 type Work @default.
- W2006642837 sameAs 2006642837 @default.
- W2006642837 citedByCount "46" @default.
- W2006642837 countsByYear W20066428372012 @default.
- W2006642837 countsByYear W20066428372013 @default.
- W2006642837 countsByYear W20066428372014 @default.
- W2006642837 countsByYear W20066428372015 @default.
- W2006642837 countsByYear W20066428372016 @default.
- W2006642837 countsByYear W20066428372017 @default.
- W2006642837 countsByYear W20066428372018 @default.
- W2006642837 countsByYear W20066428372019 @default.
- W2006642837 countsByYear W20066428372022 @default.
- W2006642837 crossrefType "journal-article" @default.
- W2006642837 hasAuthorship W2006642837A5003608252 @default.
- W2006642837 hasAuthorship W2006642837A5059960680 @default.
- W2006642837 hasConcept C118303440 @default.
- W2006642837 hasConcept C126322002 @default.
- W2006642837 hasConcept C134018914 @default.
- W2006642837 hasConcept C163170386 @default.
- W2006642837 hasConcept C170493617 @default.
- W2006642837 hasConcept C2776176026 @default.
- W2006642837 hasConcept C2776370428 @default.
- W2006642837 hasConcept C2776885963 @default.
- W2006642837 hasConcept C2777152744 @default.
- W2006642837 hasConcept C2778458438 @default.
- W2006642837 hasConcept C2779029589 @default.
- W2006642837 hasConcept C2779064019 @default.
- W2006642837 hasConcept C2779627488 @default.
- W2006642837 hasConcept C49039625 @default.
- W2006642837 hasConcept C56191518 @default.
- W2006642837 hasConcept C71315377 @default.
- W2006642837 hasConcept C71924100 @default.
- W2006642837 hasConceptScore W2006642837C118303440 @default.
- W2006642837 hasConceptScore W2006642837C126322002 @default.
- W2006642837 hasConceptScore W2006642837C134018914 @default.
- W2006642837 hasConceptScore W2006642837C163170386 @default.
- W2006642837 hasConceptScore W2006642837C170493617 @default.
- W2006642837 hasConceptScore W2006642837C2776176026 @default.
- W2006642837 hasConceptScore W2006642837C2776370428 @default.
- W2006642837 hasConceptScore W2006642837C2776885963 @default.
- W2006642837 hasConceptScore W2006642837C2777152744 @default.
- W2006642837 hasConceptScore W2006642837C2778458438 @default.
- W2006642837 hasConceptScore W2006642837C2779029589 @default.
- W2006642837 hasConceptScore W2006642837C2779064019 @default.
- W2006642837 hasConceptScore W2006642837C2779627488 @default.
- W2006642837 hasConceptScore W2006642837C49039625 @default.