FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2006647434> ?p ?o ?g. }

• W2006647434 endingPage "321" @default.
• W2006647434 startingPage "315" @default.
• W2006647434 abstract "A recombinant hybrid molecule (HM) consisting of 4 major allergens from timothy grass (Phl p 1, 2, 5, and 6) was expressed in Escherichia coli, purified, and characterized regarding its immunologic properties.We sought to determine whether the recombinant HM can be used for the diagnosis of grass pollen allergy by means of skin testing.Skin prick testing was performed in 32 patients with grass pollen allergy and in 9 control individuals by using increasing concentrations (4, 12, 36, and 108 mug/mL) of the HM and using commercial grass pollen extract. Specific IgE reactivities against the HM, grass pollen extract, and a panel of purified grass pollen allergens (recombinant Phl p 1, 2, 5, 6, 7, 12, and 13 and natural Phl p 4) were measured by means of ELISA, and timothy grass pollen-specific IgE levels were determined by using ImmunoCAP.Grass pollen allergy was diagnosed in all patients by means of skin testing with the HM. No false-positive skin test responses were obtained in the control individuals. There was an excellent correlation between IgE levels obtained with the HM and natural grass pollen extract measured by means of ELISA (r = 0.98, P < .0001) and by means of ImmunoCAP (r = 0.98, P < .0001).The recombinant HM permitted accurate and specific in vivo diagnosis of grass pollen allergy in all tested patients. It can be considered a well-defined tool for the diagnosis and perhaps for immunotherapy of grass pollen allergy.A recombinant HM can replace traditional allergen extracts for skin test-based diagnosis of grass pollen allergy." @default.
• W2006647434 created "2016-06-24" @default.
• W2006647434 creator A5012338157 @default.
• W2006647434 creator A5038469920 @default.
• W2006647434 creator A5050048947 @default.
• W2006647434 creator A5054661531 @default.
• W2006647434 creator A5065238074 @default.
• W2006647434 creator A5084819048 @default.
• W2006647434 creator A5086638886 @default.
• W2006647434 date "2007-08-01" @default.
• W2006647434 modified "2023-10-13" @default.
• W2006647434 title "Skin test diagnosis of grass pollen allergy with a recombinant hybrid molecule" @default.
• W2006647434 cites W1597634966 @default.
• W2006647434 cites W1773087570 @default.
• W2006647434 cites W1973539404 @default.
• W2006647434 cites W1984973837 @default.
• W2006647434 cites W1986190391 @default.
• W2006647434 cites W2001782786 @default.
• W2006647434 cites W2004110789 @default.
• W2006647434 cites W2009699168 @default.
• W2006647434 cites W2012266135 @default.
• W2006647434 cites W2014471812 @default.
• W2006647434 cites W2019840426 @default.
• W2006647434 cites W2029214237 @default.
• W2006647434 cites W2031154356 @default.
• W2006647434 cites W2031359883 @default.
• W2006647434 cites W2051548814 @default.
• W2006647434 cites W2055052437 @default.
• W2006647434 cites W2056261612 @default.
• W2006647434 cites W2060324747 @default.
• W2006647434 cites W2067235045 @default.
• W2006647434 cites W2067605016 @default.
• W2006647434 cites W2077337941 @default.
• W2006647434 cites W2079723175 @default.
• W2006647434 cites W2109066329 @default.
• W2006647434 cites W2171636493 @default.
• W2006647434 cites W4313333859 @default.
• W2006647434 doi "https://doi.org/10.1016/j.jaci.2007.03.046" @default.
• W2006647434 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17512042" @default.
• W2006647434 hasPublicationYear "2007" @default.
• W2006647434 type Work @default.
• W2006647434 sameAs 2006647434 @default.
• W2006647434 citedByCount "27" @default.
• W2006647434 countsByYear W20066474342012 @default.
• W2006647434 countsByYear W20066474342013 @default.
• W2006647434 countsByYear W20066474342014 @default.
• W2006647434 countsByYear W20066474342018 @default.
• W2006647434 countsByYear W20066474342019 @default.
• W2006647434 countsByYear W20066474342022 @default.
• W2006647434 crossrefType "journal-article" @default.
• W2006647434 hasAuthorship W2006647434A5012338157 @default.
• W2006647434 hasAuthorship W2006647434A5038469920 @default.
• W2006647434 hasAuthorship W2006647434A5050048947 @default.
• W2006647434 hasAuthorship W2006647434A5054661531 @default.
• W2006647434 hasAuthorship W2006647434A5065238074 @default.
• W2006647434 hasAuthorship W2006647434A5084819048 @default.
• W2006647434 hasAuthorship W2006647434A5086638886 @default.
• W2006647434 hasConcept C104317684 @default.
• W2006647434 hasConcept C141105273 @default.
• W2006647434 hasConcept C159654299 @default.
• W2006647434 hasConcept C203014093 @default.
• W2006647434 hasConcept C207480886 @default.
• W2006647434 hasConcept C2780451875 @default.
• W2006647434 hasConcept C2780510475 @default.
• W2006647434 hasConcept C2780618852 @default.
• W2006647434 hasConcept C40767141 @default.
• W2006647434 hasConcept C55493867 @default.
• W2006647434 hasConcept C59822182 @default.
• W2006647434 hasConcept C71924100 @default.
• W2006647434 hasConcept C86803240 @default.
• W2006647434 hasConceptScore W2006647434C104317684 @default.
• W2006647434 hasConceptScore W2006647434C141105273 @default.
• W2006647434 hasConceptScore W2006647434C159654299 @default.
• W2006647434 hasConceptScore W2006647434C203014093 @default.
• W2006647434 hasConceptScore W2006647434C207480886 @default.
• W2006647434 hasConceptScore W2006647434C2780451875 @default.
• W2006647434 hasConceptScore W2006647434C2780510475 @default.
• W2006647434 hasConceptScore W2006647434C2780618852 @default.
• W2006647434 hasConceptScore W2006647434C40767141 @default.
• W2006647434 hasConceptScore W2006647434C55493867 @default.
• W2006647434 hasConceptScore W2006647434C59822182 @default.
• W2006647434 hasConceptScore W2006647434C71924100 @default.
• W2006647434 hasConceptScore W2006647434C86803240 @default.
• W2006647434 hasIssue "2" @default.
• W2006647434 hasLocation W20066474341 @default.
• W2006647434 hasLocation W20066474342 @default.
• W2006647434 hasOpenAccess W2006647434 @default.
• W2006647434 hasPrimaryLocation W20066474341 @default.
• W2006647434 hasRelatedWork W1964408459 @default.
• W2006647434 hasRelatedWork W2006108005 @default.
• W2006647434 hasRelatedWork W2031458980 @default.
• W2006647434 hasRelatedWork W2072515372 @default.
• W2006647434 hasRelatedWork W2155035360 @default.
• W2006647434 hasRelatedWork W2405385860 @default.
• W2006647434 hasRelatedWork W2411933361 @default.
• W2006647434 hasRelatedWork W2414892185 @default.
• W2006647434 hasRelatedWork W2474610147 @default.
• W2006647434 hasRelatedWork W4241659254 @default.

• next