FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2006687504> ?p ?o ?g. }

• W2006687504 endingPage "1885" @default.
• W2006687504 startingPage "1875" @default.
• W2006687504 abstract "Abstract Objective: The diagnostic criteria and the clinical usefulness of the metabolic syndrome (MetSy) are currently questioned. The objective was to describe the structure of MetSy and to evaluate its components for prediction of diabetes type 2 (T2DM). Research Methods and Procedures: This was a case‐referent study nested within a population‐based health survey. Among 33,336 participants, we identified 177 initially non‐diabetic individuals who developed T2DM after 0.1 to 10.5 years (mean, 5.4 years), and, for each diabetes case, two referents matched for sex, age, and year of health survey. Baseline variables included oral glucose tolerance test, BMI, blood pressure, blood lipids, adipokines, inflammatory markers, insulin resistance, and β‐cell function. Exploratory and confirmative factor analyses were applied to hypothesize the structure of the MetSy. The prediction of T2DM by the different factors was evaluated by multivariate logistic regression analysis. Results: A hypothetical five‐factor model of intercorrelated composite factors was generated. The inflammation, dyslipidemia, and blood pressure factors were predicitive only in univariate analysis. In multivariable analyses, two factors independently and significantly predicted T2DM: an obesity/insulin resistance factor and a glycemia factor. The composite factors did not improve the prediction of T2DM compared with single variables. Among the original variables, fasting glucose, proinsulin, BMI, and blood pressure values were predictive of T2DM. Discussion: Our data support the concept of a MetSy, and we propose five separate clusters of components. The inflammation and dyslipidemia factors were not independently associated with diabetes risk. In contrast, obesity and accompanying insulin resistance and β‐cell decompensation seem to be two core perturbations promoting and predicting progression to T2DM." @default.
• W2006687504 created "2016-06-24" @default.
• W2006687504 creator A5014541444 @default.
• W2006687504 creator A5026836295 @default.
• W2006687504 creator A5027756639 @default.
• W2006687504 creator A5035554566 @default.
• W2006687504 creator A5044288681 @default.
• W2006687504 creator A5068671938 @default.
• W2006687504 creator A5070039164 @default.
• W2006687504 date "2007-07-01" @default.
• W2006687504 modified "2023-10-18" @default.
• W2006687504 title "Components of Metabolic Syndrome Predicting Diabetes: No Role of Inflammation or Dyslipidemia*" @default.
• W2006687504 cites W1505106993 @default.
• W2006687504 cites W1598025855 @default.
• W2006687504 cites W1965719439 @default.
• W2006687504 cites W1984297603 @default.
• W2006687504 cites W1996098886 @default.
• W2006687504 cites W2004224057 @default.
• W2006687504 cites W2019522333 @default.
• W2006687504 cites W2020632302 @default.
• W2006687504 cites W2024744817 @default.
• W2006687504 cites W2029897333 @default.
• W2006687504 cites W2029994787 @default.
• W2006687504 cites W2032549598 @default.
• W2006687504 cites W2050616036 @default.
• W2006687504 cites W2067601183 @default.
• W2006687504 cites W2087706636 @default.
• W2006687504 cites W2090742050 @default.
• W2006687504 cites W2091845092 @default.
• W2006687504 cites W2099498062 @default.
• W2006687504 cites W2103714496 @default.
• W2006687504 cites W2105089901 @default.
• W2006687504 cites W2107732097 @default.
• W2006687504 cites W2107810620 @default.
• W2006687504 cites W2111886196 @default.
• W2006687504 cites W2114319968 @default.
• W2006687504 cites W2117287919 @default.
• W2006687504 cites W2121879147 @default.
• W2006687504 cites W2130675894 @default.
• W2006687504 cites W2131921721 @default.
• W2006687504 cites W2132823438 @default.
• W2006687504 cites W2139623768 @default.
• W2006687504 cites W2140904803 @default.
• W2006687504 cites W2146769650 @default.
• W2006687504 cites W2151701113 @default.
• W2006687504 cites W2153214557 @default.
• W2006687504 cites W2159229970 @default.
• W2006687504 cites W2160234571 @default.
• W2006687504 cites W2163781538 @default.
• W2006687504 cites W2169121622 @default.
• W2006687504 cites W2270629577 @default.
• W2006687504 cites W2334337188 @default.
• W2006687504 cites W3033408550 @default.
• W2006687504 cites W4210956151 @default.
• W2006687504 cites W4238700990 @default.
• W2006687504 doi "https://doi.org/10.1038/oby.2007.222" @default.
• W2006687504 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17636107" @default.
• W2006687504 hasPublicationYear "2007" @default.
• W2006687504 type Work @default.
• W2006687504 sameAs 2006687504 @default.
• W2006687504 citedByCount "25" @default.
• W2006687504 countsByYear W20066875042012 @default.
• W2006687504 countsByYear W20066875042014 @default.
• W2006687504 countsByYear W20066875042016 @default.
• W2006687504 countsByYear W20066875042017 @default.
• W2006687504 countsByYear W20066875042018 @default.
• W2006687504 countsByYear W20066875042020 @default.
• W2006687504 countsByYear W20066875042022 @default.
• W2006687504 countsByYear W20066875042023 @default.
• W2006687504 crossrefType "journal-article" @default.
• W2006687504 hasAuthorship W2006687504A5014541444 @default.
• W2006687504 hasAuthorship W2006687504A5026836295 @default.
• W2006687504 hasAuthorship W2006687504A5027756639 @default.
• W2006687504 hasAuthorship W2006687504A5035554566 @default.
• W2006687504 hasAuthorship W2006687504A5044288681 @default.
• W2006687504 hasAuthorship W2006687504A5068671938 @default.
• W2006687504 hasAuthorship W2006687504A5070039164 @default.
• W2006687504 hasBestOaLocation W20066875041 @default.
• W2006687504 hasConcept C126322002 @default.
• W2006687504 hasConcept C134018914 @default.
• W2006687504 hasConcept C151956035 @default.
• W2006687504 hasConcept C2777180221 @default.
• W2006687504 hasConcept C2777391703 @default.
• W2006687504 hasConcept C2778096610 @default.
• W2006687504 hasConcept C2780578515 @default.
• W2006687504 hasConcept C2908647359 @default.
• W2006687504 hasConcept C511355011 @default.
• W2006687504 hasConcept C555293320 @default.
• W2006687504 hasConcept C71924100 @default.
• W2006687504 hasConcept C84393581 @default.
• W2006687504 hasConcept C99454951 @default.
• W2006687504 hasConceptScore W2006687504C126322002 @default.
• W2006687504 hasConceptScore W2006687504C134018914 @default.
• W2006687504 hasConceptScore W2006687504C151956035 @default.
• W2006687504 hasConceptScore W2006687504C2777180221 @default.
• W2006687504 hasConceptScore W2006687504C2777391703 @default.
• W2006687504 hasConceptScore W2006687504C2778096610 @default.
• W2006687504 hasConceptScore W2006687504C2780578515 @default.

• next