FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2006703820> ?p ?o ?g. }

• W2006703820 endingPage "257" @default.
• W2006703820 startingPage "257" @default.
• W2006703820 abstract "We had previously shown that there was a loss of sensitivity of muscarinic receptors (mAChR) to stimulation by cholinergic agonists (as assessed by examining oxotremorine enhancement of K(+)-evoked release of dopamine from neostriatal slices) in animals that had been exposed to energetic particles (56Fe, 600 MeV/n), an important component of cosmic rays. This loss of mAChR sensitivity was postulated to be the result of radiation-induced alterations in phosphoinositide-mediated signal transduction. The present experiments were undertaken as a first step toward determining the locus of these radiation-induced deficits in signal transduction by examining K+ enhancement of release of dopamine in 56Fe-exposed animals (0, 0.1, and 1.0 Gy) with agents [A23187, a potent Ca2+ ionophore, or 1,4,5-inositol trisphosphate (IP3)] that bypass the mAChR-G protein interface and by comparing the response to oxotremorine-enhanced K(+)-evoked release of dopamine. Results showed that although oxotremorine-enhanced K(+)-evoked release of dopamine was reduced significantly in the radiation groups, no radiation effects were seen when A23187 or IP3 was used to enhance K(+)-evoked release of dopamine. Since similar findings have been observed in aging, the results are discussed in terms of the parallels between aging and radiation effects in signal transduction that might exist in the neostriatum." @default.
• W2006703820 created "2016-06-24" @default.
• W2006703820 creator A5021728564 @default.
• W2006703820 creator A5022246678 @default.
• W2006703820 creator A5023974615 @default.
• W2006703820 creator A5037495241 @default.
• W2006703820 creator A5091276241 @default.
• W2006703820 date "1993-08-01" @default.
• W2006703820 modified "2023-10-16" @default.
• W2006703820 title "Deficits in the Sensitivity of Striatal Muscarinic Receptors Induced by 56 Fe Heavy-Particle Irradiation: Further Äge-Radiation Parallels" @default.
• W2006703820 cites W1775749144 @default.
• W2006703820 cites W1972760976 @default.
• W2006703820 cites W1973065125 @default.
• W2006703820 cites W1974894555 @default.
• W2006703820 cites W1985792602 @default.
• W2006703820 cites W1997093700 @default.
• W2006703820 cites W2010094123 @default.
• W2006703820 cites W2014344847 @default.
• W2006703820 cites W2024539177 @default.
• W2006703820 cites W2030926820 @default.
• W2006703820 cites W2045692472 @default.
• W2006703820 cites W2047702340 @default.
• W2006703820 cites W2054115878 @default.
• W2006703820 cites W2056620406 @default.
• W2006703820 cites W2057720151 @default.
• W2006703820 cites W2062007210 @default.
• W2006703820 cites W2064086632 @default.
• W2006703820 cites W2068468677 @default.
• W2006703820 cites W2086057482 @default.
• W2006703820 cites W2087517035 @default.
• W2006703820 cites W2092032671 @default.
• W2006703820 cites W2095456713 @default.
• W2006703820 cites W2149855017 @default.
• W2006703820 cites W2165085014 @default.
• W2006703820 cites W2322638531 @default.
• W2006703820 cites W2333088182 @default.
• W2006703820 cites W2402508046 @default.
• W2006703820 cites W206296156 @default.
• W2006703820 doi "https://doi.org/10.2307/3578303" @default.
• W2006703820 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8367598" @default.
• W2006703820 hasPublicationYear "1993" @default.
• W2006703820 type Work @default.
• W2006703820 sameAs 2006703820 @default.
• W2006703820 citedByCount "58" @default.
• W2006703820 countsByYear W20067038202013 @default.
• W2006703820 countsByYear W20067038202014 @default.
• W2006703820 countsByYear W20067038202015 @default.
• W2006703820 countsByYear W20067038202016 @default.
• W2006703820 countsByYear W20067038202017 @default.
• W2006703820 countsByYear W20067038202018 @default.
• W2006703820 countsByYear W20067038202019 @default.
• W2006703820 countsByYear W20067038202020 @default.
• W2006703820 countsByYear W20067038202021 @default.
• W2006703820 countsByYear W20067038202022 @default.
• W2006703820 countsByYear W20067038202023 @default.
• W2006703820 crossrefType "journal-article" @default.
• W2006703820 hasAuthorship W2006703820A5021728564 @default.
• W2006703820 hasAuthorship W2006703820A5022246678 @default.
• W2006703820 hasAuthorship W2006703820A5023974615 @default.
• W2006703820 hasAuthorship W2006703820A5037495241 @default.
• W2006703820 hasAuthorship W2006703820A5091276241 @default.
• W2006703820 hasConcept C120069818 @default.
• W2006703820 hasConcept C12554922 @default.
• W2006703820 hasConcept C126322002 @default.
• W2006703820 hasConcept C134018914 @default.
• W2006703820 hasConcept C169760540 @default.
• W2006703820 hasConcept C170493617 @default.
• W2006703820 hasConcept C185592680 @default.
• W2006703820 hasConcept C24998067 @default.
• W2006703820 hasConcept C2775910092 @default.
• W2006703820 hasConcept C2778824757 @default.
• W2006703820 hasConcept C33789571 @default.
• W2006703820 hasConcept C513476851 @default.
• W2006703820 hasConcept C71924100 @default.
• W2006703820 hasConcept C86803240 @default.
• W2006703820 hasConceptScore W2006703820C120069818 @default.
• W2006703820 hasConceptScore W2006703820C12554922 @default.
• W2006703820 hasConceptScore W2006703820C126322002 @default.
• W2006703820 hasConceptScore W2006703820C134018914 @default.
• W2006703820 hasConceptScore W2006703820C169760540 @default.
• W2006703820 hasConceptScore W2006703820C170493617 @default.
• W2006703820 hasConceptScore W2006703820C185592680 @default.
• W2006703820 hasConceptScore W2006703820C24998067 @default.
• W2006703820 hasConceptScore W2006703820C2775910092 @default.
• W2006703820 hasConceptScore W2006703820C2778824757 @default.
• W2006703820 hasConceptScore W2006703820C33789571 @default.
• W2006703820 hasConceptScore W2006703820C513476851 @default.
• W2006703820 hasConceptScore W2006703820C71924100 @default.
• W2006703820 hasConceptScore W2006703820C86803240 @default.
• W2006703820 hasIssue "2" @default.
• W2006703820 hasLocation W20067038201 @default.
• W2006703820 hasLocation W20067038202 @default.
• W2006703820 hasOpenAccess W2006703820 @default.
• W2006703820 hasPrimaryLocation W20067038201 @default.
• W2006703820 hasRelatedWork W145652820 @default.
• W2006703820 hasRelatedWork W1970289512 @default.
• W2006703820 hasRelatedWork W1984070948 @default.
• W2006703820 hasRelatedWork W2048194509 @default.

• next