FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2006706821> ?p ?o ?g. }

• W2006706821 endingPage "6" @default.
• W2006706821 startingPage "1" @default.
• W2006706821 abstract "Oxidative damage at the DNA level may be promoted by high levels of reactive oxygen species (ROS), leading to genomic instability and increased neoplastic risk. Superoxide dismutase (SOD), glutathione peroxidase (GPX), and catalase (CAT) enzymes are implicated in the prevention of DNA damage by ROS. The aim of the study was to investigate the relationships between CAT C262T, GPX1 Pro198Leu, MnSOD Ala16Val, GSTM1, GSTT1 , and GSTP1 Ile105Val polymorphisms and the risk of CML. No association was observed between CML and variant genotypes of GPX1, MnSOD, GSTM1 , and GSTT1 polymorphisms in any of the investigated cases. Our study suggests that the homozygous variant genotype of the GSTP1 Ile105Val gene polymorphisms may be associated with the risk of developing CML (<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M1><mml:mtext>OR</mml:mtext><mml:mo>=</mml:mo><mml:mn>2.5</mml:mn></mml:math>; 95% <mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M2><mml:mtext>CI</mml:mtext><mml:mo>=</mml:mo><mml:mn>1.08</mml:mn></mml:math>–5.7; P value = 0.02), while the heterozygous genotype of the CAT C262T polymorphism seems to have a protective effect against CML (<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M3><mml:mtext>OR</mml:mtext><mml:mo>=</mml:mo><mml:mn>0.59</mml:mn></mml:math>, 95% <mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M4><mml:mtext>CI</mml:mtext><mml:mo>=</mml:mo><mml:mn>0.39</mml:mn></mml:math>–0.89, P value = 0.01). In most cases, no association was found between laboratory parameters and prognostic factors and the variant genotype of investigated gene polymorphisms. We concluded that CAT, GPX, MnSOD, GSTM1 , and GSTT1 gene polymorphisms are not associated with the risk of CML. Variant genotype of the GSTP1 Ile105Val gene polymorphisms may contribute to the risk of developing CML." @default.
• W2006706821 created "2016-06-24" @default.
• W2006706821 creator A5016959402 @default.
• W2006706821 creator A5018718333 @default.
• W2006706821 creator A5032793277 @default.
• W2006706821 creator A5041293121 @default.
• W2006706821 creator A5041485306 @default.
• W2006706821 creator A5046217825 @default.
• W2006706821 creator A5056096167 @default.
• W2006706821 creator A5065629915 @default.
• W2006706821 creator A5088019892 @default.
• W2006706821 date "2014-01-01" @default.
• W2006706821 modified "2023-10-16" @default.
• W2006706821 title "<i>CAT, GPX1, MnSOD, GSTM1, GSTT1</i>, and<i>GSTP1</i>Genetic Polymorphisms in Chronic Myeloid Leukemia: A Case-Control Study" @default.
• W2006706821 cites W1492245366 @default.
• W2006706821 cites W1499970111 @default.
• W2006706821 cites W1975789316 @default.
• W2006706821 cites W1992688004 @default.
• W2006706821 cites W1997389433 @default.
• W2006706821 cites W2016105694 @default.
• W2006706821 cites W2022460877 @default.
• W2006706821 cites W2043142268 @default.
• W2006706821 cites W2043278476 @default.
• W2006706821 cites W2056773144 @default.
• W2006706821 cites W2127790897 @default.
• W2006706821 cites W2139923467 @default.
• W2006706821 cites W2144572305 @default.
• W2006706821 cites W2145506361 @default.
• W2006706821 cites W2150543950 @default.
• W2006706821 cites W2150559439 @default.
• W2006706821 cites W2163844911 @default.
• W2006706821 cites W2166577168 @default.
• W2006706821 cites W2168185888 @default.
• W2006706821 cites W2169886187 @default.
• W2006706821 cites W2181897273 @default.
• W2006706821 doi "https://doi.org/10.1155/2014/875861" @default.
• W2006706821 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4243135" @default.
• W2006706821 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25436036" @default.
• W2006706821 hasPublicationYear "2014" @default.
• W2006706821 type Work @default.
• W2006706821 sameAs 2006706821 @default.
• W2006706821 citedByCount "35" @default.
• W2006706821 countsByYear W20067068212015 @default.
• W2006706821 countsByYear W20067068212016 @default.
• W2006706821 countsByYear W20067068212017 @default.
• W2006706821 countsByYear W20067068212018 @default.
• W2006706821 countsByYear W20067068212019 @default.
• W2006706821 countsByYear W20067068212020 @default.
• W2006706821 countsByYear W20067068212021 @default.
• W2006706821 countsByYear W20067068212022 @default.
• W2006706821 countsByYear W20067068212023 @default.
• W2006706821 crossrefType "journal-article" @default.
• W2006706821 hasAuthorship W2006706821A5016959402 @default.
• W2006706821 hasAuthorship W2006706821A5018718333 @default.
• W2006706821 hasAuthorship W2006706821A5032793277 @default.
• W2006706821 hasAuthorship W2006706821A5041293121 @default.
• W2006706821 hasAuthorship W2006706821A5041485306 @default.
• W2006706821 hasAuthorship W2006706821A5046217825 @default.
• W2006706821 hasAuthorship W2006706821A5056096167 @default.
• W2006706821 hasAuthorship W2006706821A5065629915 @default.
• W2006706821 hasAuthorship W2006706821A5088019892 @default.
• W2006706821 hasBestOaLocation W20067068211 @default.
• W2006706821 hasConcept C104317684 @default.
• W2006706821 hasConcept C135763542 @default.
• W2006706821 hasConcept C153911025 @default.
• W2006706821 hasConcept C181199279 @default.
• W2006706821 hasConcept C185592680 @default.
• W2006706821 hasConcept C203663253 @default.
• W2006706821 hasConcept C2775838275 @default.
• W2006706821 hasConcept C2778760513 @default.
• W2006706821 hasConcept C54355233 @default.
• W2006706821 hasConcept C55493867 @default.
• W2006706821 hasConcept C86803240 @default.
• W2006706821 hasConceptScore W2006706821C104317684 @default.
• W2006706821 hasConceptScore W2006706821C135763542 @default.
• W2006706821 hasConceptScore W2006706821C153911025 @default.
• W2006706821 hasConceptScore W2006706821C181199279 @default.
• W2006706821 hasConceptScore W2006706821C185592680 @default.
• W2006706821 hasConceptScore W2006706821C203663253 @default.
• W2006706821 hasConceptScore W2006706821C2775838275 @default.
• W2006706821 hasConceptScore W2006706821C2778760513 @default.
• W2006706821 hasConceptScore W2006706821C54355233 @default.
• W2006706821 hasConceptScore W2006706821C55493867 @default.
• W2006706821 hasConceptScore W2006706821C86803240 @default.
• W2006706821 hasLocation W20067068211 @default.
• W2006706821 hasLocation W20067068212 @default.
• W2006706821 hasLocation W20067068213 @default.
• W2006706821 hasLocation W20067068214 @default.
• W2006706821 hasLocation W20067068215 @default.
• W2006706821 hasOpenAccess W2006706821 @default.
• W2006706821 hasPrimaryLocation W20067068211 @default.
• W2006706821 hasRelatedWork W1997495703 @default.
• W2006706821 hasRelatedWork W2006646123 @default.
• W2006706821 hasRelatedWork W2079838187 @default.
• W2006706821 hasRelatedWork W2080046990 @default.
• W2006706821 hasRelatedWork W2108433881 @default.
• W2006706821 hasRelatedWork W2228494489 @default.
• W2006706821 hasRelatedWork W2289315958 @default.

• next