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- W2006715728 abstract "Abstract In order to explore the mechanism by which glucocorticoid exerts an inhibitory action on glucose metabolism by adipose tissue, the effect of linkage of cortisol to agarose beads on the response of glucose utilization by rat epididymal adipose tissue to the steroid was studied. Cortisol hemisuccinyl Sepharose was shown to mimic the inhibitory activity of cortisol on glucose metabolism by adipose tissue. The activity of cortisol hemisuccinyl Sepharose was estimated as being approximately 25% that of cortisol. The linkage between cortisol hemisuccinate and amino Sepharose remained intact throughout the incubation period. These results indicate that entrance of cortisol into the cell is not a prerequisite for its action." @default.
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- W2006715728 date "1973-03-01" @default.
- W2006715728 modified "2023-09-27" @default.
- W2006715728 title "Mechanism of action of cortisol on glucose metabolism by adipose tissue" @default.
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- W2006715728 doi "https://doi.org/10.1016/0026-0495(73)90042-5" @default.
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