FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2006761570> ?p ?o ?g. }

• W2006761570 endingPage "760" @default.
• W2006761570 startingPage "756" @default.
• W2006761570 abstract "Free radicals have been implicated in the pathogenesis of neonatal sepsis and its complications. This study was conducted to determine the changes in the clinical status and the serum levels of lipid peroxidation products [malondialdehyde (MDA) and 4-hydroxylalkenals (4-HDA)] in 10 septic newborns treated with the antioxidant melatonin given within the first 12 h after diagnosis. Ten other septic newborns in a comparable state were used as “septic” controls, while 10 healthy newborns served as normal controls. A total of 20 mg melatonin was administered orally in two doses of 10 mg each, with a 1-h interval. One blood sample was collected before melatonin administration and two additional blood samples (at 1 and 4 h) were collected after melatonin administration to assess serum levels of lipid peroxidation products. Serum MDA + 4-HDA concentrations in newborns with sepsis were significantly higher than those in healthy infants without sepsis; in contrast, in septic newborns treated with melatonin there was a significant reduction (p < 0.05) of MDA + 4-HDA to the levels in the normal controls at both 1 and 4 h (p < 0.05). Melatonin also improved the clinical outcome of the septic newborns as judged by measurement of sepsis-related serum parameters after 24 and 48 h. Three of 10 septic children who were not treated with melatonin died within 72 h after diagnosis of sepsis; none of the 10 septic newborns treated with melatonin died. To our knowledge, this is the first study where melatonin was given to human newborns." @default.
• W2006761570 created "2016-06-24" @default.
• W2006761570 creator A5024021695 @default.
• W2006761570 creator A5026301783 @default.
• W2006761570 creator A5029032735 @default.
• W2006761570 creator A5037248904 @default.
• W2006761570 creator A5038954984 @default.
• W2006761570 creator A5063159500 @default.
• W2006761570 creator A5064915699 @default.
• W2006761570 creator A5071211851 @default.
• W2006761570 creator A5074289588 @default.
• W2006761570 creator A5089260642 @default.
• W2006761570 date "2001-12-01" @default.
• W2006761570 modified "2023-10-18" @default.
• W2006761570 title "Effects of Melatonin Treatment in Septic Newborns" @default.
• W2006761570 cites W1612547865 @default.
• W2006761570 cites W1972296635 @default.
• W2006761570 cites W1974357471 @default.
• W2006761570 cites W1975025234 @default.
• W2006761570 cites W1977427213 @default.
• W2006761570 cites W1982707171 @default.
• W2006761570 cites W1983372750 @default.
• W2006761570 cites W2012149358 @default.
• W2006761570 cites W2019993857 @default.
• W2006761570 cites W2020709143 @default.
• W2006761570 cites W2024805528 @default.
• W2006761570 cites W2033819095 @default.
• W2006761570 cites W2034132165 @default.
• W2006761570 cites W2039292117 @default.
• W2006761570 cites W2055988844 @default.
• W2006761570 cites W2090517643 @default.
• W2006761570 cites W2098619885 @default.
• W2006761570 cites W2104511643 @default.
• W2006761570 cites W2144757596 @default.
• W2006761570 cites W2171722927 @default.
• W2006761570 cites W90011462 @default.
• W2006761570 doi "https://doi.org/10.1203/00006450-200112000-00021" @default.
• W2006761570 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11726736" @default.
• W2006761570 hasPublicationYear "2001" @default.
• W2006761570 type Work @default.
• W2006761570 sameAs 2006761570 @default.
• W2006761570 citedByCount "438" @default.
• W2006761570 countsByYear W20067615702012 @default.
• W2006761570 countsByYear W20067615702013 @default.
• W2006761570 countsByYear W20067615702014 @default.
• W2006761570 countsByYear W20067615702015 @default.
• W2006761570 countsByYear W20067615702016 @default.
• W2006761570 countsByYear W20067615702017 @default.
• W2006761570 countsByYear W20067615702018 @default.
• W2006761570 countsByYear W20067615702019 @default.
• W2006761570 countsByYear W20067615702020 @default.
• W2006761570 countsByYear W20067615702021 @default.
• W2006761570 countsByYear W20067615702022 @default.
• W2006761570 countsByYear W20067615702023 @default.
• W2006761570 crossrefType "journal-article" @default.
• W2006761570 hasAuthorship W2006761570A5024021695 @default.
• W2006761570 hasAuthorship W2006761570A5026301783 @default.
• W2006761570 hasAuthorship W2006761570A5029032735 @default.
• W2006761570 hasAuthorship W2006761570A5037248904 @default.
• W2006761570 hasAuthorship W2006761570A5038954984 @default.
• W2006761570 hasAuthorship W2006761570A5063159500 @default.
• W2006761570 hasAuthorship W2006761570A5064915699 @default.
• W2006761570 hasAuthorship W2006761570A5071211851 @default.
• W2006761570 hasAuthorship W2006761570A5074289588 @default.
• W2006761570 hasAuthorship W2006761570A5089260642 @default.
• W2006761570 hasBestOaLocation W20067615701 @default.
• W2006761570 hasConcept C126322002 @default.
• W2006761570 hasConcept C134018914 @default.
• W2006761570 hasConcept C2776151105 @default.
• W2006761570 hasConcept C2778182776 @default.
• W2006761570 hasConcept C2778384902 @default.
• W2006761570 hasConcept C2778401633 @default.
• W2006761570 hasConcept C2780829032 @default.
• W2006761570 hasConcept C42219234 @default.
• W2006761570 hasConcept C42407357 @default.
• W2006761570 hasConcept C71924100 @default.
• W2006761570 hasConcept C90924648 @default.
• W2006761570 hasConceptScore W2006761570C126322002 @default.
• W2006761570 hasConceptScore W2006761570C134018914 @default.
• W2006761570 hasConceptScore W2006761570C2776151105 @default.
• W2006761570 hasConceptScore W2006761570C2778182776 @default.
• W2006761570 hasConceptScore W2006761570C2778384902 @default.
• W2006761570 hasConceptScore W2006761570C2778401633 @default.
• W2006761570 hasConceptScore W2006761570C2780829032 @default.
• W2006761570 hasConceptScore W2006761570C42219234 @default.
• W2006761570 hasConceptScore W2006761570C42407357 @default.
• W2006761570 hasConceptScore W2006761570C71924100 @default.
• W2006761570 hasConceptScore W2006761570C90924648 @default.
• W2006761570 hasIssue "6" @default.
• W2006761570 hasLocation W20067615701 @default.
• W2006761570 hasLocation W20067615702 @default.
• W2006761570 hasOpenAccess W2006761570 @default.
• W2006761570 hasPrimaryLocation W20067615701 @default.
• W2006761570 hasRelatedWork W2019556559 @default.
• W2006761570 hasRelatedWork W2024177211 @default.
• W2006761570 hasRelatedWork W2040985455 @default.
• W2006761570 hasRelatedWork W2155244507 @default.
• W2006761570 hasRelatedWork W2163243996 @default.

• next