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- W2006765416 abstract "The proliferative response of sensitized human T cells to low concentrations of purified protein derivative of tuberculin (PPD) in vitro has previously been shown to depend on the presence of autologous or HLA-D-compatible macrophages (M phi). In this paper we present evidence that the M phi/T cell interaction requires viable M phi and does not involve a soluble factor. T cells from neonates do not respond to PPD in our system, while M phi from neonates are able to present PPD to T cells from HLA-D matched sensitized adults. It is also demonstrated that the previously reported HLA-D restriction of T cell/M phi cooperation is not due to T cell mediated killing of allogeneic macrophages in vitro." @default.
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- W2006765416 date "1979-06-01" @default.
- W2006765416 modified "2023-09-24" @default.
- W2006765416 title "Macrophage/T-Lymphocyte Interaction in the Immune Response to PPD in Humans" @default.
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- W2006765416 doi "https://doi.org/10.1111/j.1365-3083.1979.tb03279.x" @default.
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