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- W2006771864 abstract "Antiphospholipid syndrome (APS) is frequently associated with uteroplacental circulation insufficiency leading to pregnancy complications, such as fetal loss, fetal growth restriction (IUGR), preeclampsia and thrombosis. The purpose of this study was to examine the relationship between Doppler flow parameters of the spiral artery (SA) and pregnancy outcome in women with pregnancies complicated by antiphospholipid syndrome. We examined 50 women with normal pregnancy and 28 women with pregnancy complicated by ASP. All pregnancies were singleton and were followed-up to the delivery. Spiral artery Doppler flow measurements (pulsatility index (PI) and resistance index (RI) were performed using transabdominal probe between 18 to 22 weeks of gestation. The ultrasound probe was positioned in vagina to visualize the hypoechoic parts of retroplacental area. Maternal spiral arteries were identified as having low-resistance, turbulent arterial flow. Obtained data were analyzed with paired Student's t-test. All patients with normal pregnancies delivered healthy fetuses at term. In the group of pregnant women with ASP—2 (7.1%) miscarriages were noted, 8 (28.6%) pregnancies were complicated by IUGR and 7 (25.0%) pregnancies were complicated by preeclampsia. Ultrasound Doppler parameters of spiral arteries obtained in both groups were compared. Significant differences in the PI values for maternal spiral artery were found: 2.38 ± 1.14 in normal pregnancies versus 1.64 ± 0.98 (P < 0.05) in ASP group. No significant differences were found between the values of resistance index in normal and ASP groups (0.88 ± 0.28 and 1.12 ± 0.25 respectively). High pulsatility index of subchorionic spiral arteries was significant higher in pregnancies with antiphospholipid syndrome." @default.
- W2006771864 created "2016-06-24" @default.
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- W2006771864 date "2010-10-01" @default.
- W2006771864 modified "2023-09-27" @default.
- W2006771864 title "P24.13: Color Doppler ultrasound of spiral artery blood flow assessment in women with antiphospholipid syndrome" @default.
- W2006771864 doi "https://doi.org/10.1002/uog.8641" @default.
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