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- W2006810504 abstract "Among the different metabolites of o-toluidine only the nitroso and hydroxylamino derivatives were found to be very potent frameshift mutagens in the presence of the co-mutagen norharman and S9. In the absence of norharman and S9 they are only base pair mutagens. Norharman failed to evoke the mutagenicity of the non-carcinogenic m- and p-toluidine and their respective nitroso and hydroxylamino metabolites. This report highlights that norharman plays a role in the appearance of mutagenicity of certain carcinogenic amines and metabolites." @default.
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- W2006810504 date "1989-07-01" @default.
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- W2006810504 title "Effect of norharman on the mutagenicity of toluidine metabolites" @default.
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- W2006810504 doi "https://doi.org/10.1016/0378-4274(89)90188-4" @default.
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