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- W2006851467 abstract "The genetic properties of strain K/2002, isolated from fecal samples of a 7-month-old child who had received his first oral poliovirus vaccine (OPV) dose at the age of 3 months, are described. Preliminary sequencing characterization of isolate K/2002 revealed an S3/S2 recombination event at the 3′ end of the VP1 coding region. A recombination event resulted in the introduction of six Sabin 2 amino acid residues in a Sabin 3 genomic background. Furthermore, mutations associated with loss of the attenuated phenotype of Sabin 3 strains have been identified in the genome of isolate K/2002. The data presented here emphasize the need for careful planning of vaccination strategies, which involve stopping OPV administration in regions that are certified to be polio-free." @default.
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- W2006851467 date "2008-04-01" @default.
- W2006851467 modified "2023-09-28" @default.
- W2006851467 title "Complete genomic characterization of an intertypic Sabin 3/Sabin 2 capsid recombinant" @default.
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- W2006851467 doi "https://doi.org/10.1111/j.1574-695x.2008.00381.x" @default.
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