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- W2006874407 abstract "Analysis of the subcellular location of the proteins encoded by the oncogenes of avian myeloblastosis virus and avian leukemia virus E26 (p45v-myb and p135gag-myb-ets, respectively) and by the chicken c-myb gene (p75c-myb) shows that all three proteins are located in the nucleus. In AMV-infected (but not transformed) chicken fibroblasts p45v-myb also resides in the nucleus, indicating that a nuclear location of p45v-myb in these cells is not sufficient to achieve transformation. In AMV-transformed mye-loblasts a small fraction of p45v-myb occupies an additional site in the perinuclear region of the cytoplasm. If the myeloblasts are caused to differentiate to macrophages, most of p45v-myb is found in the cytoplasm. This redistribution of p45v-myb within the cell may be responsible for reversion of the transformed phenotype." @default.
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- W2006874407 date "1984-06-01" @default.
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- W2006874407 title "Subcellular localization of proteins encoded by oncogenes of avian myeloblastosis virus and avian leukemia virus E26 and by the chicken c-myb gene" @default.
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