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- W2006930306 abstract "Background Argon plasma coagulation (APC) has been used to ablate Barrett’s oesophagus, although the long-term efficacy is unknown. This study reports the 5 year results of APC ablation vs surveillance of Barrett’s in post-fundoplication patients.Methods 43 post-fundoplication patients with Barrett’s oesophagus were randomised to either APC ablation of Barrett’s or surveillance. 40 have been followed up with endoscopic surveillance for a mean of 68 months to assess treatment efficacy, safety and the durability of the neosquamous re-epithelialisation.Results A median of 2.5 (range 1–6) APC treatment sessions was required to reach >95% ablation of Barrett’s. Both groups had a significant (p 95% ablation of their Barrett’s, with 8 of 14 (57%) having no macroscopic or histologic evidence of Barrett’s. 4 of 20 surveillance patients (20%) had complete reversal of their Barrett’s, with 3 of 4 (75%) having no macroscopic or histologic evidence for Barrett’s. 2 patients in the APC group developed strictures requiring dilation. 2 patients in the surveillance group developed HGD during follow-up, while none did in the APC group.Conclusions 40% of post-fundoplication patients with APC ablation of Barrett’s retain this reversal beyond 5 years. 20% of Barrett’s patients post-fundoplication regress to normal squamous mucosa. Post-fundoplication Barrett’s surveillance patients continue to develop HGD, this has not been seen in the APC group." @default.
- W2006930306 created "2016-06-24" @default.
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- W2006930306 date "2007-05-01" @default.
- W2006930306 modified "2023-10-16" @default.
- W2006930306 title "HP22 FIVE YEAR RESULTS OF A PROSPECTIVE RANDOMISED CONTROLLED TRIAL OF ARGON PLASMA COAGULATION VS ENDOSCOPIC SURVEILLANCE OF PATIENTS WITH BARRETT?S OESOPHAGUS AFTER ANTIREFLUX SURGERY" @default.
- W2006930306 doi "https://doi.org/10.1111/j.1445-2197.2007.04122_22.x" @default.
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