Matches in SemOpenAlex for { <https://semopenalex.org/work/W2006932846> ?p ?o ?g. }
Showing items 1 to 68 of
68
with 100 items per page.
- W2006932846 endingPage "1698" @default.
- W2006932846 startingPage "1689" @default.
- W2006932846 abstract "SUMMARY Six commonly used strains of lymphocytic choriomeningitis virus (LCMV) [Armstrong (Arm) CA 1371, Arm E-350, WE, UBC, Traub and Pasteur C1PV 76001] were examined for distinctive genetic and biological properties. Agarose gel electrophoresis yielded no detectable differences among the L or S RNAs of these six strains. The RNase T1 fingerprint patterns of LCMV Arm CA 1371 and E-350 RNAs were similar, but in contrast, those of the WE, UBC, Traub and Pasteur strains differed from each other and from the pattern of LCMV Arm CA 1371 and E-350. There were also differences among LCMV strains in their biological properties. LCMV Arm CA 1371, E-350 and Pasteur caused severe vasculitis and focal necrotizing hepatitis in the livers of neonatally infected BALB/WEHI mice in contrast to LCMV WE which caused minimal lesions. LCMV Arm CA 1371 and E-350 were lethal for neonatal C3H/St mice. In contrast, LCMV WE, Traub and Pasteur induced persistent infections in C3H/St mice. Adult guinea-pigs resisted infection by Arm CA 1371, E-350, Traub and Pasteur but succumbed to WE and UBC LCMV strains. Our results show a wide variation in the RNA genomes of LCMV strains commonly used in research laboratories, and these genomic differences are accompanied by variations in the biological properties of LCMV strains." @default.
- W2006932846 created "2016-06-24" @default.
- W2006932846 creator A5001380638 @default.
- W2006932846 creator A5012010485 @default.
- W2006932846 date "1983-08-01" @default.
- W2006932846 modified "2023-10-18" @default.
- W2006932846 title "Genomic and Biological Variation among Commonly Used Lymphocytic Choriomeningitis Virus Strains" @default.
- W2006932846 doi "https://doi.org/10.1099/0022-1317-64-8-1689" @default.
- W2006932846 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6875516" @default.
- W2006932846 hasPublicationYear "1983" @default.
- W2006932846 type Work @default.
- W2006932846 sameAs 2006932846 @default.
- W2006932846 citedByCount "232" @default.
- W2006932846 countsByYear W20069328462012 @default.
- W2006932846 countsByYear W20069328462013 @default.
- W2006932846 countsByYear W20069328462014 @default.
- W2006932846 countsByYear W20069328462015 @default.
- W2006932846 countsByYear W20069328462016 @default.
- W2006932846 countsByYear W20069328462017 @default.
- W2006932846 countsByYear W20069328462018 @default.
- W2006932846 countsByYear W20069328462019 @default.
- W2006932846 countsByYear W20069328462020 @default.
- W2006932846 countsByYear W20069328462021 @default.
- W2006932846 countsByYear W20069328462022 @default.
- W2006932846 crossrefType "journal-article" @default.
- W2006932846 hasAuthorship W2006932846A5001380638 @default.
- W2006932846 hasAuthorship W2006932846A5012010485 @default.
- W2006932846 hasBestOaLocation W20069328461 @default.
- W2006932846 hasConcept C106358424 @default.
- W2006932846 hasConcept C147483822 @default.
- W2006932846 hasConcept C159047783 @default.
- W2006932846 hasConcept C167672396 @default.
- W2006932846 hasConcept C2522874641 @default.
- W2006932846 hasConcept C2779574689 @default.
- W2006932846 hasConcept C2780190958 @default.
- W2006932846 hasConcept C54355233 @default.
- W2006932846 hasConcept C86803240 @default.
- W2006932846 hasConceptScore W2006932846C106358424 @default.
- W2006932846 hasConceptScore W2006932846C147483822 @default.
- W2006932846 hasConceptScore W2006932846C159047783 @default.
- W2006932846 hasConceptScore W2006932846C167672396 @default.
- W2006932846 hasConceptScore W2006932846C2522874641 @default.
- W2006932846 hasConceptScore W2006932846C2779574689 @default.
- W2006932846 hasConceptScore W2006932846C2780190958 @default.
- W2006932846 hasConceptScore W2006932846C54355233 @default.
- W2006932846 hasConceptScore W2006932846C86803240 @default.
- W2006932846 hasIssue "8" @default.
- W2006932846 hasLocation W20069328461 @default.
- W2006932846 hasLocation W20069328462 @default.
- W2006932846 hasOpenAccess W2006932846 @default.
- W2006932846 hasPrimaryLocation W20069328461 @default.
- W2006932846 hasRelatedWork W161837088 @default.
- W2006932846 hasRelatedWork W168521517 @default.
- W2006932846 hasRelatedWork W1975803895 @default.
- W2006932846 hasRelatedWork W2031361508 @default.
- W2006932846 hasRelatedWork W2108003884 @default.
- W2006932846 hasRelatedWork W2237091872 @default.
- W2006932846 hasRelatedWork W2424288746 @default.
- W2006932846 hasRelatedWork W2556485530 @default.
- W2006932846 hasRelatedWork W2785673800 @default.
- W2006932846 hasRelatedWork W4296311675 @default.
- W2006932846 hasVolume "64" @default.
- W2006932846 isParatext "false" @default.
- W2006932846 isRetracted "false" @default.
- W2006932846 magId "2006932846" @default.
- W2006932846 workType "article" @default.