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- W2006933530 abstract "Restriction site maps with the endonucleases BamHI, BgIII, and HindIII were elaborated for 19 adenovirus strains of subgenus D, namely candidates AV42 to 47, 6 intermediate and 7 atypical strains. On the basis of several types mapped by biochemical methods, the physical maps for the 19 strains were constructed by adapting restriction fragments of defined molecular weight to the known maps, as the homology among strains within this subgenus is considerable. Other prototypes mapped by adaptation were also used for reference (16). The localization of the restriction sites on the genome was analyzed for all mapped types or strains of subgenus D (except AV8). The sites appeared to be randomly distributed; only one site was common to all strains. Restriktionskarten mit den Enzymen BamHI, BgIII und HindIII wurden fur 19 Adenovirusstämme von Subgenus D erarbeitet, und zwar für die “Prototyp-Kandidaten” AV42 — AV47, 6 Intermediär- und 7 atypische Stämme. Auf der Grundlage mehrerer Typen, die mit biochemischen Methoden kartiert sind, wurden die physikalischen Karten für die 19 Stämme durch Adaptation ihrer Restriktionsfragmente von bekanntem Molekulargewicht konstruiert, was in Anbetracht der beträchtlichen genetischen Homologie vertretbar ist. Andere Prototypen, die ebenfalls durch Adaptation kartiert wurden (16), haben wir zum Vergleich herangezogen. Die Lokalisation der Schnittstellen (“sites”) auf dem Genom wurde für alle kartierten Typen und Stämme von Subgenus D (außer AV8) analysiert. Die Schnittstellen sind offenbar statistisch verteilt: nur eine war allen Stämmen gemeinsam." @default.
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- W2006933530 date "1991-12-01" @default.
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- W2006933530 title "Restriction Site Mapping of Subgenus D Adenoviruses, Prototypes 42–47, Intermediate and Atypical Strains" @default.
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- W2006933530 doi "https://doi.org/10.1016/s0934-8840(11)80224-0" @default.
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